1313591-15-9Relevant academic research and scientific papers
Selenochromanes via tandem homolytic addition/substitution chemistry
Staples, Maree K.,Schiesser, Carl H.
, p. 565 - 567 (2010)
Selenochromanes and analogues are conveniently prepared through a tandem homolytic addition/substitution sequence involving suitably substituted olefins.
GPx-like activity of selenides and selenoxides: Experimental evidence for the involvement of hydroxy perhydroxy selenane as the active species
Nascimento, Vanessa,Alberto, Eduardo E.,Tondo, Daniel W.,Dambrowski, Daniel,Detty, Michael R.,Nome, Faruk,Braga, Antonio L.
supporting information; experimental part, p. 138 - 141 (2012/03/07)
The reaction mechanism of the GPx-like oxidation of PhSH with H 2O2 catalyzed by selenoxides proceeds via formation of the hydroxy perhydroxy selenane, which is a stronger oxidizing agent than selenoxide. A hydroxy perhydroxy selenan
Selenoether ligand assisted Heck catalysis
Chakraborty, Tapash,Srivastava, Kriti,Singh, Harkesh B.,Butcher, Ray J.
experimental part, p. 2559 - 2564 (2011/07/09)
Selenoether ligands, 2,2′-methylenebis(selanediyl)bis(2,1-phenylene) dimethanol (5), (2,2′-(ethane-1,2-diylbis(selanediyl))bis(2,1-phenylene)) dimethanol (6) and (2-(benzylselanyl)phenyl)methanol (7) have been synthesized by reducing di-o-formylphenyl diselenide and reacting the in situ generated selenolate with dibromomethane, 1,2-dibromoethane and benzyl chloride, respectively. The ligands, bis(2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl) phenylselanyl)methane (8) and 1,2-bis(2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl) phenylselanyl)ethane (9) have been synthesized similarly from bis[2-(4,4-dimethyl-2-oxazolinyl)phenyl] diselenide using electrophiles dibromomethane and 1,2-dibromoethane, respectively. Activity of ligands 5-9 along with 2-(2-(benzylselanyl)phenyl)-4,4-dimethyl-4,5-dihydrooxazole (10) and 1-(2-(benzylselanyl)phenyl)-N,N-dimethylmethanamine (11) were examined for the Heck reaction of aryl halides with olefins. Bidentate Se,N ligand 11 was found to be the best one in the series and constitutes an efficient phosphine-free catalytic system with PdCl2. The catalytic system showed moderate activity for the coupling of activated aryl chlorides in the presence of tetra-n-butyl ammonium bromide (TBAB). Complexes [10-PdCl2] (12) and [11-PdCl2] (13) have shown marginally better activity in comparison to the in situ generated catalysts from PdCl2 and 10 and 11, respectively in the coupling of 4-bromoacetophenone with n-butylacrylate. Ligand 9 and complex 13 have been characterized by single crystal X-ray diffraction analysis.
