131368-29-1Relevant articles and documents
Bisphosphonates derived from fatty acids are potent growth inhibitors of Trypanosoma cruzi
Szajnman, Sergio H.,Bailey, Brian N.,Docampo, Roberto,Rodriguez, Juan B.
, p. 789 - 792 (2001)
We have investigated the effect of a series of bisphosphonates derived from fatty acids against Trypanosoma cruzi proliferation in in vitro assays. Some of these drugs proved to be potent inhibitors against the intracellular form of the parasite exhibiting IC50 values at the low micromolar level. As bisphosphonates are FDA clinically approved for treatment of bone resorption, their potential innocuousness makes them good candidates to control tropical diseases.
Studies on hydrolysis of chiral, achiral and racemic alcohol esters with Pseudomonas cepacia lipase: mechanism of stereospecificity of the enzyme
Nishizawa, Kanji,Ohgami, Yasutaka,Matsuo, Noritada,Kisida, Hiroshi,Hirohara, Hideo
, p. 1293 - 1298 (2007/10/03)
Steady-state kinetics of Pseudomonas cepacia lipase-catalysed hydrolysis of five analogues chiral and achiral substrates, i.e. (R)- and (S)-1-methyl-2-(4-phenoxyphenoxy)ethyl acetates (R)- and (S)-1a, (R)- and (S)-2-methyl-2-(4-phenoxyphenoxy)ethyl acetat
