1313714-59-8Relevant articles and documents
Substituted pyrimidinedione compound and application thereof
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Paragraph 0155; 0157-0161, (2020/11/25)
The invention belongs to the technical field of medicines, and relates to a substituted pyrimidinedione compound and application thereof, and a pharmaceutical composition containing the compound, which can be used as a gonadotropin releasing hormone receptor antagonist. The invention also relates to a method for preparing the compound and the pharmaceutical composition, and application of the compound and the pharmaceutical composition in prevention or treatment of sex hormone dependent diseases including but not limited to prostate cancer, endometriosis, hysteromyoma, precocious puberty and the like.
Heterocyclyl-substituted thieno[2,3-d]pyrimidine-2,4-(1H,3H)-diketone compound and application thereof
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Paragraph 0141-0146, (2020/11/22)
The invention belongs to the technical field of medicines, and relates to heterocyclyl-substituted thieno[2,3-d]pyrimidine-2,4-(1H,3H)-diketone compounds and application thereof, and a pharmaceuticalcomposition containing the compounds; wherein the compounds and the pharmaceutical composition can be used as gonadotropin releasing hormone receptor antagonists. The invention also relates to a method for preparing the compound and the pharmaceutical composition, and application of the compounds and the pharmaceutical compositions in prevention or treatment of sex hormone dependent diseases, including but not limited to: prostate cancer, endometriosis, hysteromyoma, precocious puberty and the like.
Nitrogen-containing heteroaryl substituted pyrimidinedione compound and application thereof
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Paragraph 0130; 0135; 0137-0139, (2020/11/25)
The invention belongs to the technical field of medicines, and relates to a nitrogen-containing heteroaryl substituted pyrimidinedione compound and application thereof, and a pharmaceutical composition containing the compound, and the nitrogen-containing heteroaryl substituted pyrimidinedione compound and the pharmaceutical composition can be used as gonadotropin releasing hormone receptor antagonists. The invention also relates to a method for preparing the compound and the pharmaceutical composition, and application of the compound and the pharmaceutical composition in prevention or treatment of sex hormone dependent diseases including but not limited to prostate cancer, endometriosis, hysteromyoma, precocious puberty and the like.