1313738-72-5

Basic information

• Product Name: 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine
• Synonyms: 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine;1-[(2-fluorophenyl)methyl]-3-iodo-1H-pyrazolo[3,4-b]pyridine
• CAS NO: 1313738-72-5
• Molecular Formula: C₁₃H₉FIN₃
• Molecular Weight: 353.1335332
• Mol File: 1313738-72-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 451.1±40.0 °C(Predicted)
• Appearance: /
• Density: 1.79±0.1 g/cm3(Predicted)
• PKA: 2.11±0.30(Predicted)
• CAS DataBase Reference: 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine(1313738-72-5)
• EPA Substance Registry System: 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine(1313738-72-5)

Safety Data

• Hazardous Substances Data: 1313738-72-5(Hazardous Substances Data)

Usage

General Description

1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine is a chemical compound with a complex molecular structure. It is a heterocyclic compound containing a pyrazole ring fused to a pyridine ring, with fluorine and iodine substitutions at specific positions. 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine may have potential applications in medicinal chemistry, particularly in the development of new drugs and pharmaceuticals. The specific combination of functional groups and the unique structure of 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine may make it a valuable scaffold for the design and synthesis of biologically active compounds for various therapeutic purposes. Further research and development of this compound could yield valuable insights and potential new treatments for a range of diseases and medical conditions.

Upstream product

• 446-48-0 o-fluorobenzyl bromide 
• 117007-52-0 3-iodo-1H-pyrazolo[3,4-b]pyridine 

Downstream Products

• 1361570-38-8 6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyridine-2,3-diamine 
• 1361570-49-1 2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-6-methylpyrimidine-4,5-diamine 
• 1361570-57-1 Ethyl 5,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4-carboxylate 
• 1361570-64-0 methyl {4-amino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-6-methylpyrimidin-5-yl}carbamate formate 
• 1361569-43-8 6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2-methylpyrido[2,3-b]pyrazin-3(4H)-one 
• 1361569-44-9 6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-2-isopropylpyrido[2,3-b]pyrazin-3(4H)-one 
• 1361569-45-0 6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrido[2,3-b]pyrazine 
• 1361569-48-3 5-[1-(2-fluorobenzyl)-1H-pyrazolo [3,4-b]pyridin-3-yl]-1,3-dihydro-2H-imidazo [4,5-b]pyridin-2-one 
• 1361569-71-2 5-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-1,3-dihydro-2H-imidazo[4,5-b]pyrazin-2-one 
• 1361569-89-2 2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-6-(hydroxymethyl)-7,9-dihydro-8H-purin-8-one 
• 1361569-92-7 ethyl 2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-8-oxo-8,9-dihydro-7H-purine-6-carboxylate 
• 1361569-93-8 2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-6-methyl-7,9-dihydro-8H-purin-8-one 
• 1361570-11-7 6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine 
• 1361570-37-7 6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-3-nitropyridin-2-amine 

Relevant articles and documents

METHOD FOR SYNTHESIZING 1-(2-FLUOROBENZYL)-1H-PYRAZOLO[3,4-B]PYRIDINE-3-FORMAMIDINE HYDROCHLORIDE

The present invention relates to the field of chemical synthesis, and in particular to a method for synthesizing 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-formamidine hydrochloride, which is an important intermediate of Riociguat that is an anti-thro