1313757-63-9Relevant academic research and scientific papers
A convenient synthesis of new chromophoric tetracyanobutadiene-scaffolded peptides via a dipolar [2+2] cycloaddition-cycloreversion reaction
Rijkers, Dirk T.S.,Diederich, Fran?ois
, p. 4021 - 4025 (2011/08/21)
Herein, we report a novel approach for the synthesis of π-conjugated peptide-based donor-acceptor (D-π-A) chromophores, by reacting electron-rich alkynes with tetracyanoethylene. The desired tetracyanobutadiene-scaffolded peptides were obtained in good yields with various optical properties, λmax: 321-492 nm, ε: 21,000-65,000 mol-1 dm3 cm-1 depending on the substitution pattern of the cyanobutadiene scaffold.
