13138-53-9

Basic information

• Product Name: 4-Nitrophthaldiamide
• Synonyms: 1,2-BENZENEDICARBOXAMIDE,4-NITRO-;4-NITROPHTHALAMIDE;4-Nitrophthaldiamide;4-NITROPHTHALIC ACID DIAMIDE;4-nitro-2-benzenedicarboxamide;Nitrophthalamide,98%;4-Nitrophthaldiamid;4-NITROPHTHALAMIDE 99%
• CAS NO: 13138-53-9
• Molecular Formula: C₈H₇N₃O₄
• Molecular Weight: 209.16
• EINECS: 236-070-6
• Product Categories: N;Stains and Dyes;Stains&Dyes, A to
• Mol File: 13138-53-9.mol
• Article Data: 13

Chemical Properties

• Melting Point: 195 °C (dec.)(lit.)
• Boiling Point: 418.496 °C at 760 mmHg
• Flash Point: 206.899 °C
• Appearance: /
• Density: 1.508 g/cm³
• Vapor Pressure: 3.27E-07mmHg at 25°C
• Refractive Index: 1.651
• Storage Temp.: room temp
• CAS DataBase Reference: 4-Nitrophthaldiamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Nitrophthaldiamide(13138-53-9)
• EPA Substance Registry System: 4-Nitrophthaldiamide(13138-53-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 1
• Hazardous Substances Data: 13138-53-9(Hazardous Substances Data)

Usage

Uses

4-Nitrophthalamide is a stain/dye. Dyes and metabolites.

Synthesis

30 g (0.156 mol) 4-nitrophthalimide was stirred in 168 mL 32% ammonia solution for 24 hours. Then it was filtered, washed with cold water, and tetrahydrofuran (THF). The color of phthalimide was yellow and it turned to white as reaction proceeds. Molecular formula: C8H7N3O4. Yield: 24 g (73%). Mp: 197 °C.

InChI:InChI=1/C8H7N3O4/c9-7(12)5-2-1-4(11(14)15)3-6(5)8(10)13/h1-3H,(H2,9,12)(H2,10,13)

Upstream product

• 89-40-7 4-nitrophthalimide 
• 24564-72-5 4-nitrophthalic acid chloride 
• 610-27-5 4-nitrophthalic acid 
• 136918-14-4 phthalimide 
• 90072-77-8 4-nitro-phthalic acid-1-methyl ester 

Downstream Products

• 89-40-7 4-nitrophthalimide 
• 31643-49-9 4-Nitrophthalonitrile 
• 475088-99-4 1,2-bis(3,4-dicyanophenoxymethyl)-benzene 
• 1402060-55-2 4-[(4'-carboxy)phenylamino]phthalonitrile 
• 1190088-71-1 4-(prop-2-yn-1-yloxy)phthalonitrile 
• 31643-50-2 4-(N-acetylamino)phthalonitrile 
• 125023-53-2 6-(p-cumylphenoxy)-1,3-dihydro-1,3-diiminoisoindole 
• 83482-57-9 4-[4-(1-methyl-1-phenylethyl)phenoxy]-1,2-dicyanobenzene 
• 125023-52-1 6-(p-tert-butylphenoxy)-1,3-dihydro-1,3-diiminoisoindole 
• 125023-51-0 4-(4–tert-butylphenoxy) phthalonitrile 
• 96917-81-6 4-isobutoxyphthalonitrile 
• 126388-92-9 2-cyano-4-nitrobenzoic acid 
• 23277-29-4 Bis<3,4-dicyanophenyl> ether 
• 30757-50-7 4-hydroxy-1,2-benzenedicarbonitrile 

Relevant articles and documents

Preparation of new biologically active and water soluble dyes: Characterization, aggregation and extraction of metal ions from solutions

The synthesis of metallo-phthalocyanines complexes (M = Co, Ni, Cu, Zn) containing azo dye were described in this study. The metallophthalocyanines have been supported by elemental analysis, UV-visible, FT-IR and NMR. The aggregation of phthalocyanine compounds was investigated in different solvents and concentrations. The newly synthesized metallophthalocyanines possess modest antibacterial activity against various Gram-positive and Gram-negative bacteria. Moreover, these complexes have been tested as antioxidant and presented remarkable activities by two different in vitro chemical assays. They were able to reduce DPPH % radical with IC50 values ranging from 3.8 to 7.5 μmol L-1 and some of them also reduced ABTS % radical cation.

Novel aqueous soluble cobalt(II) phthalocyanines of tetracarboxyl-substituted: Synthesis and catalytic activity on oxidation of sodium diethyldithiocarbamate

Enhancement of the catalytic activity of phthalocyanine catalysts by immobilizing them on polymer matrix has been studied. It has been found that the immobilization of cobalt(II) phthalocyanines on polymers enhances their catalytic activity in the oxidation of sodium diethyldithiocarbamate by air oxygen under mild conditions.

Preparation of 1,2-bis(3,4-dicyanophenoxymethyl)benzene and the binuclear zinc phthalocyanine derived from it

A method of synthesis of 1,2-bis(3,4-dicyanophenoxymethyl)benzene from the 1,2-bis(hydroxymethyl)benzene and 4-nitrophthalodinitrile is developed. Its tetramerization with Zn(OAc)2·2H2O gives a binuclear zinc phthalocyanine of a new type, containing four o-phenylidene bridges. The use of microwave heating decreases reaction time and increases yield.