3558-18-7

Basic information

• Product Name: 2-(ACETYLAMINO)-5-NITROBENZOIC ACID
• Synonyms: 2-(ACETYLAMINO)-5-NITROBENZOIC ACID;2-ACETAMIDO-5-NITROBENZOIC ACID;2-(Acetylamino)-5-nitrobenzoic acid , 90+%
• CAS NO: 3558-18-7
• Molecular Formula: C₉H₈N₂O₅
• Molecular Weight: 224.17
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acids;Phenyls & Phenyl-Het;Carboxylic Acids;Phenyls & Phenyl-Het
• Mol File: 3558-18-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 215 °C
• Boiling Point: 501.7 °C at 760 mmHg
• Flash Point: 257.2 °C
• Appearance: /
• Density: 1.526 g/cm³
• Vapor Pressure: 6.9E-11mmHg at 25°C
• Refractive Index: 1.656
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(ACETYLAMINO)-5-NITROBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(ACETYLAMINO)-5-NITROBENZOIC ACID(3558-18-7)
• EPA Substance Registry System: 2-(ACETYLAMINO)-5-NITROBENZOIC ACID(3558-18-7)

Safety Data

• Hazardous Substances Data: 3558-18-7(Hazardous Substances Data)

Usage

General Description

2-(Acetylamino)-5-nitrobenzoic acid is an organic compound with the chemical formula C9H8N2O4. It is classified as a derivative of benzoic acid and is commonly used in the synthesis of pharmaceuticals and organic dyes. This chemical compound is known for its yellow to orange color and is soluble in organic solvents. It is also used as an intermediate in the production of various types of drugs and has been studied for its anti-microbial properties. The nitro group in the molecule makes it a potential candidate for further research in the development of novel pharmaceuticals and other applications.

InChI:InChI=1/C9H8N2O5/c1-5(12)10-8-3-2-6(11(15)16)4-7(8)9(13)14/h2-4H,1H3,(H,10,12)(H,13,14)

Upstream product

• 2719-15-5 2-methyl-4-nitroacetanilide 
• 108-24-7 acetic anhydride 
• 616-79-5 2-amino-5-nitro-benzoic acid 
• 13138-53-9 4-nitrophthalic amide 
• 99-52-5 2-methyl-4-nitro-benzenamine 
• 118-92-3 anthranilic acid 
• 91538-60-2 N-(2-formyl-4-nitrophenyl)acetamide 
• 120-66-1 N-(2-methylphenyl)acetamide 
• 7697-37-2 nitric acid 
• 89-52-1 o-acetylamino-benzoic acid 
• 10073-89-9 2-methyl-6-nitro-4H-benzo[d][1,3]oxazin-4-one 
• 7732-18-5 water 

Downstream Products

• 100-01-6 4-nitro-aniline 
• 1194506-70-1 C₁₇H₁₁ClN₄O₂ 
• 123524-74-3 2-mercapto-3-(2',4'-dichlorostilbenyl)-6-nitro-4-oxoquinazoline 
• 616-79-5 2-amino-5-nitro-benzoic acid 
• 123524-73-2 2-mercapto-6-nitro-3-(4-methyl-phenyl)quinazolin-4(3H)-one 
• 54669-98-6 2-Acetylamino-5-amino-benzoic acid 

Relevant articles and documents

NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND BENAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME

Disclosed are compounds represented by formula (I) which have triglyceride biosynthesis inhibitory activity in the liver and inhibitory activity against the secretion of apolipoprotein B-containing lipoprotein from the liver and particularly have excellent inhibitory activity against the secretion of apolipoprotein B-containing lipoprotein, are free from side effect of accumulation of lipids in the liver, and are useful for the treatment and prevention of hyperlipidemia and arteriosclerotic diseases. In formula (I), R1 and R2 represent alkyl, alkoxy, cycloalkyl, phenyl, alkenyl, alkynyl, or a five- or six-membered saturated or unsaturated heterocyclic ring, or R1 and R2, together with a nitrogen atom to which R1 and R2 are attached, may form a ring; R3 and R4 represent a hydrogen atom, alkyl, a halogen atom, hydroxyl, nitrile, alkoxycarbonyl, alkoxy, or carboxyl; or R2 and R3 may be attached to each other to form -(CH2)m-, -N=CH-, -CH=N-, or -(C1-6 alkyl)C=N-; A, D, E, and G each represent a carbon atom, or any one of A, D, E, and G represents a nitrogen atom with the other three each representing a carbon atom; Q represents a nitrogen atom or a carbon atom; Y represents a group represented by formula (II) wherein X represents a hydrogen atom, group -C(=O)N(R5)R6 or group -C(=O)OR7, R8 is absent or represents a bond, an oxygen atom, a sulfur atom, -SO2-, -SO-, -CH2-CH2-, or - CH=CH-, and R9 and R10 represent a hydrogen atom, alkyl, alkoxy, a halogen atom, or hydroxyl; and Z represents - (CH2)n-, -O-(CH2)i-, or -C(=O)NH-(CH2)i-.

Diaminopuridine-containing thiourea inhibitors of herpes viruses

Compounds of the formula STR1 are useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and -7, and Kaposi herpesvirus.