131380-84-2Relevant academic research and scientific papers
A highly active palladium(II)-bis(oxazoline) catalyst for Suzuki-Miyaura, Mizoroki-Heck and sonogashira coupling reactions in aqueous dimethylformamide
Ibrahim, Mansur B.,El Ali, Bassam,Fettouhi, Mohammed,Ouahab, Lahcène
, p. 400 - 407 (2015)
An efficient catalytic system based on a new palladium-bis(oxazoline) (Pd-BOX-1) complex has been developed. The complex Pd-BOX-1 adopts a legless chair-type structure where the distorted square planar [PdN2Cl2] moiety and the benzene ring spacer represent the seat and the chair back, respectively. The catalytic activity of Pd-BOX-1 has been investigated in dimethylformamide-water under aerobic and mild conditions in Suzuki-Miyaura coupling reactions of arylboronic acids with aryl iodides, aryl bromides and aryl chlorides, Mizoroki-Heck coupling reactions of aryl halides with styrene derivatives, and Sonogashira coupling reactions of aryl halides with terminal alkynes. A wide range of functional groups as substituents on the arylboronic acids and aryl halides were considered. Pd-BOX-1 demonstrates exceptional air and moisture stability. Of note, the catalyst system based on Pd-BOX-1 shows high recycling ability in Suzuki-Miyaura coupling reactions in dimethylformamide-water without any loss in catalytic activity.
A facile one stage synthesis of oxazolines under microwave irradiation
Clarke, David S.,Wood, Robin
, p. 1335 - 1340 (1996)
A rapid, high yielding procedure for the synthesis of 2-substituted oxazolines has been achieved under microwave irradiation from alkyl and aryl nitriles and β-amino alcohols using a mild Lewis acid catalyst.
Palladium(II) complex for catalyzing sonogashira coupling reactions and a method thereof
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Page/Page column 13, (2017/02/09)
A palladium(II) complex which catalyzes the Sonogashira coupling reaction efficiently under aerobic condition and a method of employing the palladium(II) complex to synthesize internal alkynes. The palladium(II) complex is an effective catalyst for the co
Amino oxazolines as easily accessible water stable ligands for palladium catalysed aqueous Heck reaction
Saiyed, Akeel S.,Joshi, Reshma S.,Bedekar, Ashutosh V.
experimental part, p. 408 - 411 (2011/10/08)
A series of amino oxazolinyl ligands were screened for palladium catalysed Heck reaction. These ligands work well as phosphine free system in aqueous, micellar medium, can be effectively recovered and reused for subsequent cycles.
Natural Kaolinitic clay catalyzed conversion of nitriles to 2-oxazolines
Jnaneshwara,Deshpande,Lalithambika,Ravindranathan,Bedekar
, p. 459 - 462 (2007/10/03)
Natural Kaolinitic clay has been found effective as catalyst in the conversion of aromatic and aliphatic nilriles with 1,2-aminoalcohol to 2-oxazolines (56-96%, yield).
Synthesis of Optically Active Bis(2-oxazolines): Crystal Structure of a 1,2-Bis(2-oxazolinyl)benzene * ZnCl2 Complex
Bolm, Carsten,Weickhardt, Konrad,Zehnder, Margareta,Ranff, Tobias
, p. 1173 - 1180 (2007/10/02)
Dinitriles (5-7, 12, 13) react with enantiomerically pure β-amino alcohols (8-11, 17) under zinc chloride catalysis to give optically active C2-symmetric bis(oxazolines). 1,2-Bis(2-oxazolin-2-yl)benzenes 1a-e are obtained under mild reaction conditions. 1H-NMR spectroscopy indicates the formation of 1:1 complexes 23 of these compounds with ZnCl2.The energy required for a conformational interconversion of zinc dichloride complex 23e was determined by variable-temperature 1H-NMR studies.An X-ray structure analysis was performed with the substituted zinc dichloride complex 23a.
