131387-85-4Relevant academic research and scientific papers
Stereoselective synthesis of trans-4,5-substituted 1,4,5,6-tetrahydropyridine-2-(olates)thiolates
Shestopalov,Litvinov,Rodinovskaya,Sharanin Yu.
, p. 402 - 404 (2007/10/02)
trans-4,5-Substituted 1,4,5,6-tetrahydropyridine-2-(olates)thiolates are prepared either from pyridinium salts and cyanoacetic acid derivatives or from pyridinium salts, aromatic aldehydes and ethyl cyanoacetate or cyanoacetamide in the presence of a base
THE CYCLIZATION REACTIONS OF NITRILES. XXXVI. THE REACTIONS OF FUNCTIONAL DERIVATIVES OF CYANOACETIC ACID WITH 1-STYRYLPYRIDINIUM SALTS AND THE STEREOCHEMISTRY OF THE FORMATION OF 4-ARYL-2-OXO-3-(1-PYRIDINO)-5-CYANO-3,4-TRANS-1,2,3,4-TETRAHYDRO-6-PYRIDINO
Shestopalov, A. M.,Sharanin, Yu. A.,Rodinovskaya, L. A.,Litvinov, V. P.
, p. 1356 - 1361 (2007/10/02)
The addition of cyanoacetic acid derivatives to 1-styrylpyridinium salts proceeds stereoselectively with the formation of anti-conformers of pyridinium 1,4-ylids, which also cyclize stereoselectively to give 4-aryl-2-oxo-3-(1-pyridino)-5-cyano-3,4-trans-1
