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CAS

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1313885-05-0

2-(4-chlorophenyl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)ethanamine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1313885-05-0 Structure

  • Basic information

    1. Product Name: 2-(4-chlorophenyl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)ethanamine
    2. Synonyms: 2-(4-chlorophenyl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)ethanamine
    3. CAS NO:1313885-05-0
    4. Molecular Formula:
    5. Molecular Weight: 289.848
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1313885-05-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(4-chlorophenyl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)ethanamine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(4-chlorophenyl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)ethanamine(1313885-05-0)
    11. EPA Substance Registry System: 2-(4-chlorophenyl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)ethanamine(1313885-05-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1313885-05-0(Hazardous Substances Data)

1313885-05-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1313885-05-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,3,8,8 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1313885-05:
(9*1)+(8*3)+(7*1)+(6*3)+(5*8)+(4*8)+(3*5)+(2*0)+(1*5)=150
150 % 10 = 0
So 1313885-05-0 is a valid CAS Registry Number.

1313885-05-0Relevant articles and documents

CXCR3 antagonists: Quaternary ammonium salts equipped with biphenyl- and polycycloaliphatic-anchors

Wijtmans, Maikel,Verzijl, Dennis,Bergmans, Serge,Lai, Michael,Bosch, Leontien,Smit, Martine J.,De Esch, Iwan J.P.,Leurs, Rob

, p. 3384 - 3393 (2011)

Small-molecule ligands for the CXCR3 chemokine receptor receive considerable attention as a means to interrogate the roles of CXCR3 in vitro and in vivo and/or to potentially treat various conditions such as inflammatory diseases and cancer. We have synthesized and explored a novel class of small-molecule antagonists for CXCR3. A medium-throughput screen revealed an adamantane-guanidine as a hit. The guanidine unit was replaced by a small quaternary ammonium group, leading to ca. 5-fold increase in affinity. Substitution of the adamantane group by a myrtenyl moiety further increased affinity, while the benzyl group was decorated with an additional (substituted) aryl ring. This led to the identification of several bisaryl-based ligands with CXCR3 affinities of around 100 nM and with the ability to antagonize the functional activity of CXCL10.

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