1313892-05-5Relevant articles and documents
Design, synthesis, and evaluation of bromo-retrochalcone derivatives as protein tyrosine phosphatase 1B inhibitors
Liu, Zhiguo,Lee, Woojung,Kim, Su-Nam,Yoon, Goo,Cheon, Seung Hoon
, p. 3755 - 3758 (2011)
A series of bromo-retrochalcones was designed, synthesized and evaluated as PTP1B inhibitors based on licochalcone A and E. Compounds 6, 12, 13, 14, 25, 36, 37, 39, and 41 showed potent inhibitory effects against PTP1B, and compound 37, the most potent am