Bioorganic and Medicinal Chemistry Letters p. 3755 - 3758 (2011)
Update date:2022-07-29
Topics:
Liu, Zhiguo
Lee, Woojung
Kim, Su-Nam
Yoon, Goo
Cheon, Seung Hoon
A series of bromo-retrochalcones was designed, synthesized and evaluated as PTP1B inhibitors based on licochalcone A and E. Compounds 6, 12, 13, 14, 25, 36, 37, 39, and 41 showed potent inhibitory effects against PTP1B, and compound 37, the most potent am
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Doi:10.1007/s12032-021-01530-w
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(2011)