1314033-46-9Relevant academic research and scientific papers
N,N′-Dioxide-nickel(II) complex catalyzed asymmetric Michael addition of cyclic 1,3-dicarbonyl compounds to β,γ-unsaturated α-ketoesters
Dong, Zhenhua,Feng, Juhua,Cao, Weidi,Liu, Xiaohua,Lin, Lili,Feng, Xiaoming
, p. 3433 - 3436 (2011)
A direct asymmetric Michael addition of cyclic 1,3-dicarbonyl compounds to β,γ-unsaturated α-ketoesters could be efficiently catalyzed by an N,N′-dioxide-nickel(II) complex. A series of chiral warfarin derivatives were obtained in excellent yields (up to 99%) with high enantioselectivities (up to 90% ee) under mild conditions within shorter reaction time.
