1314033-57-2Relevant articles and documents
Enantioselective asymmetric michael addition of cyclic diketones to β,γ-unsaturated α-keto esters
Wang, Yi-Feng,Wang, Ke,Zhang, Wei,Zhang, Bin-Bin,Zhang, Chi-Xiao,Xu, Dan-Qian
, p. 3691 - 3696 (2012)
An efficient, organocatalytic enantioselective addition of cyclic diketones with β,γ-unsaturated α-keto esters has been developed that affords products in high yields (up to 95%) and excellent enantioselectivity (up to >99ee) under mild conditions with a
Bifunctional Amine-Squaramides as Organocatalysts in Michael/Hemiketalization Reactions of β,γ-Unsaturated α-Ketoesters and α,β-Unsaturated Ketones with 4-Hydroxycoumarins
Modrocká, Viktória,Veverková, Eva,Me?iarová, Mária,?ebesta, Radovan
, p. 13111 - 13120 (2018/10/25)
The catalytic efficiency of various amine-squaramides was tested in Michael/hemiketalization reactions of 4-hydroxycoumarines with two types of enones. Tertiary amine-squaramide organocatalysts afforded the best results regarding both activity and enantio
Enantioselective synthesis of coumarins catalyzed by a bifunctional amine-thiourea catalyst
Gao, Yaojun,Ren, Qiao,Wang, Lei,Wang, Jian
supporting information; experimental part, p. 13068 - 13071 (2011/02/21)
Efficient excess: An efficient and facile enantioselective Michael addition reaction through hydrogen-bonding catalysis for the synthesis of coumarin complexes has been developed (see scheme). A simple bifunctional amine-thiourea small molecule has been discovered to catalyze this process with high yields and high to excellent enantiomeric excesses.
