1314035-52-3Relevant academic research and scientific papers
Sialic acid C-glycosides with aromatic residues: Investigating enzyme binding and inhibition of Trypanosoma cruzi trans-sialidase
Meinke, Sebastian,Schroven, Andreas,Thiem, Joachim
, p. 4487 - 4497 (2011)
Several α-configured C-sialosides were synthesised by cross metathesis and further synthetic derivatisation to obtain ligands for Trypanosoma cruzi trans-sialidase (TcTS), a key enzyme in Chagas disease. Affinities of these compounds to immobilised TcTS w
