1314097-19-2Relevant academic research and scientific papers
Microwave-mediated synthesis of a cyclic heptapeptoid through consecutive Ugi reactions
Barreto, Angélica de Fátima S.,Andrade, Carlos Kleber Z.
, p. 6861 - 6865 (2018/10/24)
The combination of consecutive Isocyanide-based Multicomponent Reactions (IMCRs) allowed the synthesis of a cyclic heptapeptoid in a reduced number of steps. Herein, we describe this efficient approach using four consecutive Ugi reactions, being three Ugi
Fast and efficient microwave-assisted synthesis of functionalized peptoids via Ugi reactions
Barreto, Angelica De Fatima S.,Vercillo, Otilie E.,Birkett, Mike A.,Caulfield, John C.,Wessjohann, Ludger A.,Andrade, Carlos Kleber Z.
, p. 5024 - 5027 (2011/08/21)
A wide range of N-alkylglycines (peptoids) can be efficiently prepared via Ugi reactions using microwave irradiations. The results confirm the versatility and efficiency of the methodology for the preparation of functionalized peptoids. The products can be used in consecutive Ugi reactions to yield cyclic peptoids of potential biological interest. The Royal Society of Chemistry 2011.
