13142-49-9Relevant academic research and scientific papers
A Cu-Promoted C-N Coupling of Boron Esters and Diaziridinone: An Approach to Aryl Ureas
Li, Jing,Wang, Xiaoyu,Wang, Zhanwei,Shi, Yian
, p. 8958 - 8962 (2021/11/24)
A novel Cu-promoted C-N coupling between boron esters and di-tert-butyldiaziridinone is described. A wide variety of aryl ureas can be readily obtained under mild conditions with up to a 92% yield.
Metal-free synthesis of pyridin-2-yl ureas from 2-aminopyridinium salts
Saroj,Patel, Om P.S.,Rangan, Krishnan,Kumar, Anil
, (2019/07/23)
An unprecedented base promoted domino approach has been developed for the synthesis of pyridin-2-yl urea derivatives via the reaction of 2-aminopyridinium salts and arylamines. The developed strategy tolerated a wide range of functional groups and afforded pyridin-2-yl ureas in moderate to good yields. The reaction was postulated to involve tandem cyclization, intermolecular nucleophilic addition, ring opening, and demethylation.
