13142-79-5Relevant academic research and scientific papers
Synthetic method and application of urea compound
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Paragraph 0046-0049, (2019/06/07)
The invention relates to a synthetic method of a urea compound, comprising the following steps: adding substituted oxazolone and sodium acetate into a methanol solution, and adding substituted amine under the stirring condition, reacting and carrying out column chromatography to obtain the urea compound. The defect that dangerous compounds need to be used during existing synthetic process is overcome, and a one-pot method is adopted to replace an existing reaction with low yield. The method of the invention has mild reaction condition, the operation is simple, raw materials are easily available, and the substrate can be converted into various other useful molecules. The compound has strong practicality, and can be applied to synthesis of the pesticide daimuron, dieresis long and the anti-cancer drug Sorafenib. The invention relates to a green and environmentally-friendly unsymmetrical urea compound synthesis method with simple process and low cost.
Synthesis and studies of a super-structured porphyrin derivative - A potential building block for CcO mimic models
Charalambidis, Georgios,Ladomenou, Kalliopi,Boitrel, Bernard,Coutsolelos, Athanassios G.
experimental part, p. 1263 - 1268 (2009/07/19)
A novel porphyrin complex that contains an Fe porphyrin linked to a tridentate ligand where a Cu ion could be coordinated was synthesized. The molecule also incorporated a tyrosine mimic attached to the porphyrin ring via a urea bond and was fully charact
