1314238-79-3Relevant academic research and scientific papers
A catalyst-free, three-component decarboxylative coupling of amino acids with aldehydes and H-dialkylphosphites for the synthesis of α- aminophosphonates
Kaboudin, Babak,Karami, Leila,Kato, Jun-Ya,Aoyama, Hiroshi,Yokomatsu, Tsutomu
supporting information, p. 4872 - 4875 (2013/09/02)
A simple, efficient, and new method is developed for the synthesis of α-aminophosphonates via a three-component, catalyst-free decarboxylative coupling of amino acids with aldehydes and H-dialkyl phosphite. Treatment of amino acids with aldehydes and diethyl phosphite in the absence of catalyst, base, and ligand give α-aminophosphonates in moderate to good yields. This method is simple, rapid, and high-yielding.
Copper/DIPEA-catalyzed, aldehyde-induced tandem decarboxylation-coupling of natural α-amino acids and phosphites or secondary phosphine oxides
Yang, Dongxu,Zhao, Depeng,Mao, Lijuan,Wang, Linqing,Wang, Rui
experimental part, p. 6426 - 6431 (2011/09/15)
A copper/DIPEA-catalyzed, aldehyde-induced intermolecular decarboxylative coupling reaction of natural α-amino acids and phosphites or secondary phosphine oxides was developed. In this process, a series of potentially useful ligands for organic synthesis
