131432-92-3

Basic information

• Product Name: (2S)-N-benzyl-2-bromopropanamide
• Synonyms: (2S)-N-Benzyl-2-bromopropanamide; propanamide, 2-bromo-N-(phenylmethyl)-, (2S)-
• CAS NO: 131432-92-3
• Molecular Formula: C₁₀H₁₂BrNO
• Molecular Weight: 242.1124
• Mol File: 131432-92-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 380.4°C at 760 mmHg
• Flash Point: 183.9°C
• Density: 1.385g/cm³
• Vapor Pressure: 5.45E-06mmHg at 25°C
• Refractive Index: 1.558
• CAS DataBase Reference: (2S)-N-benzyl-2-bromopropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-N-benzyl-2-bromopropanamide(131432-92-3)
• EPA Substance Registry System: (2S)-N-benzyl-2-bromopropanamide(131432-92-3)

Safety Data

• Hazardous Substances Data: 131432-92-3(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 306972-98-5 3-Bromo-4-methoxyphenyl (S)-2-bromopropanoate 
• 6653-71-0 N-benzyl-2-bromopropanamide 
• 124-63-0 methanesulfonyl chloride 
• 535-11-5 Ethyl 2-bromopropionate 

Downstream Products

• 6653-72-1 (S)-N-benzyl-2-diethylaminopropanamide 
• 6653-72-1 (R)-N-benzyl-2-diethylaminopropanamide 
• 131335-55-2 (R)-N-benzyl-2-(benzylamino)propanamide 
• 132198-10-8 (S)-N,N'-dibenzylalaninamide 
• 24752-67-8 (S)-N-benzyl-2-tert-butylaminopropanamide 
• 24752-67-8 (R)-N-benzyl-2-tert-butylaminopropanamide 

Relevant articles and documents

A simple enantioconvergent and chemoenzymatic synthesis of optically active α-substituted amides

Simple and efficient: The combination of an enzymatic, enantioinverting reaction with simple follow-up processes allows the transformation of readily available racemic compounds into versatile chiral α-substituted amides (see picture; Ms=methanesulfonyl).

Lipase catalysed synthesis of optically enriched α-haloamides

An efficient lipase catalysed synthesis of optically enriched α-halogenated amides with concomitant optical enrichment of the starting α-haloesters is described. Candida antarctica lipase (CAL) was found to be a better catalyst over porcine pancreatic lipase (PPL) and Candida cylindracea lipase (CCL). The effect of different organic solvents was also studied.