1314324-85-0

Basic information

• Product Name: N-(4-methoxy-1H-benzo[d]imidazol-7-yl)-3,5-dichloro-4-hydroxylbenzenesulfonamide
• CAS NO: 1314324-85-0
• Molecular Weight: 388.231
• Mol File: 1314324-85-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-methoxy-1H-benzo[d]imidazol-7-yl)-3,5-dichloro-4-hydroxylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methoxy-1H-benzo[d]imidazol-7-yl)-3,5-dichloro-4-hydroxylbenzenesulfonamide(1314324-85-0)
• EPA Substance Registry System: N-(4-methoxy-1H-benzo[d]imidazol-7-yl)-3,5-dichloro-4-hydroxylbenzenesulfonamide(1314324-85-0)

Safety Data

• Hazardous Substances Data: 1314324-85-0(Hazardous Substances Data)

Upstream product

• 1314324-70-3 4-methoxy-7-nitro-1H-benzo[d]imidazole 
• 1314324-71-4 4-methoxy-7-amino-1H-benzo[d]imidazole 
• 13432-81-0 3,5-dichloro-4-hydroxybenzene-1-sulfonyl chloride 
• 37466-89-0 3-methoxybenzene-1,2-diamine 
• 603-85-0 2-Amino-3-nitrophenol 
• 16554-45-3 2-methoxy-6-nitroaniline 
• 27080-53-1 4-methoxy-1H-benzo[d]imidazole 

Relevant articles and documents

Synthesis and cytotoxic evaluation of N-(4-methoxy-1H-benzo[d]imidazol-7- yl)-arylsulfonamide and N-aryl-(4-methoxy-1H-benzo[d]imidazol)-7-sulfonamide analogs of combretastatin A-4

Two series of novel benzoimidazole sulfonamides as combretastatin A-4 analogs were synthesized. The cytotoxicities of the title compounds were evaluated against five different cancer cell lines. Among the tested compounds, four compounds displayed cytotoxicities against the HCT8 cell line. Compound 6a has shown the strongest potency against the tested human tumor cell lines with an IC50 value ranging from submicromolar to micromolar level.