13144-62-2

Basic information

• Product Name: N-CYCLOHEXYL-OXALAMIC ACID
• Synonyms: N-CYCLOHEXYL-OXALAMIC ACID;(cyclohexylamino)(oxo)acetic acid;acetic acid, (cyclohexylamino)oxo-;Albb-009497;(cyclohexylamino)(oxo)acetic acid(SALTDATA: FREE);2-(cyclohexylamino)-2-keto-acetic acid;2-(cyclohexylamino)-2-oxoacetic acid;2-(cyclohexylamino)-2-oxo-acetic acid
• CAS NO: 13144-62-2
• Molecular Formula: C₈H₁₃NO₃
• Molecular Weight: 171.19
• Mol File: 13144-62-2.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• Density: 1.2g/cm³
• Refractive Index: 1.507
• CAS DataBase Reference: N-CYCLOHEXYL-OXALAMIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: N-CYCLOHEXYL-OXALAMIC ACID(13144-62-2)
• EPA Substance Registry System: N-CYCLOHEXYL-OXALAMIC ACID(13144-62-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 13144-62-2(Hazardous Substances Data)

Usage

General Description

N-cyclohexyl-oxalamic acid is a chemical compound with the molecular formula C10H17NO3. Also known as CHOX, this compound is used as a scale inhibitor in water treatment processes to prevent the buildup of mineral deposits. It is an effective anti-scaling agent, particularly in applications where calcium carbonate scaling is a concern. CHOX works by binding to minerals in the water, preventing them from forming solid deposits on surfaces such as pipes and heat exchangers. The compound is stable under normal conditions and is commonly used in industrial and commercial water treatment systems to maintain efficient and reliable operation.

InChI:InChI=1/C8H13NO3/c10-7(8(11)12)9-6-4-2-1-3-5-6/h6H,1-5H2,(H,9,10)(H,11,12)

Upstream product

• 108-91-8 cyclohexylamine 
• 4755-77-5 Ethyl oxalyl chloride 
• 39183-54-5 ethyl 2-(cyclohexylamino)-2-oxoacetate 
• 86072-19-7 methyl N-cyclohexyloxamate 
• 95-92-1 oxalic acid diethyl ester 
• 553-90-2 Dimethyl oxalate 

Downstream Products

• 1040762-86-4 C₂₁H₁₈BrClF₃N₃O₃ 
• 63483-22-7 3-chloropropyl cyclohexylcarbamate 
• 17671-80-6 butyl N-cyclohexylcarbamate 
• 5817-68-5 cyclohexyl-carbamic acid methyl ester 
• 418795-69-4 N-cyclohexyl-3-(trifluoromethyl)benzamide 
• 59507-55-0 3-bromo-N-cyclohexylbenzamide 
• 57707-20-7 4-chloro-N-cyclohexylbenzamide 
• 114691-95-1 4-acetyl-N-(cyclohexyl)benzamide 
• 223553-87-5 N-(cyclohexyl)-4-bromobenzamide 

Relevant articles and documents

Supporting-Electrolyte-Free Anodic Oxidation of Oxamic Acids into Isocyanates: An Expedient Way to Access Ureas, Carbamates, and Thiocarbamates

We report a new electrochemical supporting-electrolyte-free method for synthesizing ureas, carbamates, and thiocarbamates via the oxidation of oxamic acids. This simple, practical, and phosgene-free route includes the generation of an isocyanate intermediate in situ via anodic decarboxylation of an oxamic acid in the presence of an organic base, followed by the one-pot addition of suitable nucleophiles to afford the corresponding ureas, carbamates, and thiocarbamates. This procedure is applicable to different amines, alcohols, and thiols. Furthermore, when single-pass continuous electrochemical flow conditions were used and this reaction was run in a carbon graphite Cgr/Cgr flow cell, urea compounds could be obtained in high yields within a residence time of 6 min, unlocking access to substrates that were inaccessible under batch conditions while being easily scalable.

Urethanes synthesis from oxamic acids under electrochemical conditions

Urethane synthesis via oxidative decarboxylation of oxamic acids under mild electrochemical conditions is reported. This simple phosgene-free route to urethanes involves an in situ generation of isocyanates by anodic oxidation of oxamic acids in an alcoholic medium. The reaction is applicable to a wide range of oxamic acids, including chiral ones, and alcohols furnishing the desired urethanes in a one-pot process without the use of a chemical oxidant.

Metal-, Photocatalyst-, and Light-Free Direct C-H Acylation and Carbamoylation of Heterocycles

Direct C-H acylations and carbamoylations of heterocycles can now be readily achieved without requiring any conventional metal, photocatalyst, electrocatalysis, or light activation, thus significantly improving on sustainability, costs, toxicity, waste, and simplicity of the operational procedure. These mild conditions are also suitable for gram-scale reactions and late-stage functionalizations of complex molecules, including pharmaceuticals, N,N-ligands, and light-sensitive molecules.