1314532-15-4Relevant academic research and scientific papers
FeCl3·6H2O-catalyzed synthesis of substituted cis-2,6-tetrahydropyrans from ζ-hydroxy allylic derivatives
Guérinot, Amandine,Serra-Muns, Anna,Bensoussan, Charlélie,Reymond, Sébastien,Cossy, Janine
, p. 5024 - 5033 (2011)
A highly diastereoselective iron-catalyzed synthesis of substituted cis-2,6-tetrahydropyrans from ζ-hydroxy allylic derivatives is described. The FeCl3·6H2O-induced epimerization of the formed 2-alkenyl 6-substituted tetrahydropyrans is the key reaction to account for the high diastereoselectivities observed.
