1314532-22-3

Upstream product

• 1221972-05-9 acetic acid 1-(2,4,6-trimethyl-phenyl)-allyl ester 
• 1221972-32-2 acetic acid 1-pentyl-hex-5-enyl ester 
• 487-68-3 mesytaldehyde 
• 1014982-70-7 undec-1-en-6-ol 

Downstream Products

• 1221972-34-4 (E)-1-(2,4,6-trimethyl-phenyl)-dodec-2-ene-1,7-diol 

Relevant academic research and scientific papers

FeCl3·6H2O-catalyzed synthesis of substituted cis-2,6-tetrahydropyrans from ζ-hydroxy allylic derivatives

A highly diastereoselective iron-catalyzed synthesis of substituted cis-2,6-tetrahydropyrans from ζ-hydroxy allylic derivatives is described. The FeCl3·6H2O-induced epimerization of the formed 2-alkenyl 6-substituted tetrahydropyrans is the key reaction to account for the high diastereoselectivities observed.

FeCl3-catalyzed highly diastereoselective synthesis of substituted piperidines and tetrahydropyrans

The eco-friendly and highly diastereoselective synthesis of substituted cis-2,6-piperidines and cis-2,6-tetrahydropyrans is described. The key step of this method is the iron-catalyzed thermodynamic equilibration of 2-alkenyl 6-substituted piperidines and 2-alkenyl 6-substituted tetrahydropyrans allowing the isolation of enriched mixtures of the most stable cis-isomers.