1221972-05-9

Upstream product

• 1051488-22-2 1-(2,4,6-trimethylphenyl)prop-2-en-1-ol 
• 108-24-7 acetic anhydride 
• 487-68-3 mesytaldehyde 
• 1826-67-1 vinyl magnesium bromide 

Downstream Products

• 1233144-56-3 acetic acid (E)-3-(2,4,6-trimethyl-phenyl)-allyl ester 
• 1221972-35-5 (E)-1-(2,4,6-trimethyl-phenyl)-dodec-1-ene-3,7-diol 
• 1221972-34-4 (E)-1-(2,4,6-trimethyl-phenyl)-dodec-2-ene-1,7-diol 
• 1314532-22-3 C₂₅H₃₈O₄ 
• 1221972-37-7 (E)-8-methyl-1-(2,4,6-trimethyl-phenyl)-non-2-ene-1,7-diol 
• 1314532-33-6 cis-(2R,6R)-2-methyl-6-((E)-2,4,6-trimethylstyryl)tetrahydropyran 
• 1314532-16-5 (E)-(1RS,7R)-1-(2,4,6-trimethylphenyl)-oct-2-ene-1,7-diol 

Relevant academic research and scientific papers

FeCl3·6H2O-catalyzed synthesis of substituted cis-2,6-tetrahydropyrans from ζ-hydroxy allylic derivatives

A highly diastereoselective iron-catalyzed synthesis of substituted cis-2,6-tetrahydropyrans from ζ-hydroxy allylic derivatives is described. The FeCl3·6H2O-induced epimerization of the formed 2-alkenyl 6-substituted tetrahydropyrans is the key reaction to account for the high diastereoselectivities observed.

Silica gel-mediated rearrangement of allylic acetates. Application to the synthesis of 1,3-enynes

Silica gel was found to efficiently promote the rearrangement of allylic acetates into their most stable regioisomers under microwave irradiation. The reaction is easy to perform and eco-friendly. This method was applied to the metal-free synthesis of 1,3-enynes.

FeCl3-catalyzed highly diastereoselective synthesis of substituted piperidines and tetrahydropyrans

The eco-friendly and highly diastereoselective synthesis of substituted cis-2,6-piperidines and cis-2,6-tetrahydropyrans is described. The key step of this method is the iron-catalyzed thermodynamic equilibration of 2-alkenyl 6-substituted piperidines and 2-alkenyl 6-substituted tetrahydropyrans allowing the isolation of enriched mixtures of the most stable cis-isomers.