1314534-89-8

Upstream product

• 114085-00-6 2-amino-3-cyano-4-trifluoro-methyl-6-phenyl-pyridine 
• 64-19-7 acetic acid 
• 130880-72-7 2-amino-6-phenyl-4-(trifluoromethyl)nicotinamide 
• 123-54-6 acetylacetone 
• 3335-44-2 2-oxo-6-phenyl-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile 

Downstream Products

• 1314535-12-0 2-methyl-7-phenyl-3-((1-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-1H-1,2,3-triazol-4-yl)methyl)-5-(trifluoromethyl) pyrido[2,3-d]pyrimidine-4(3H)-one 
• 1314535-13-1 3-((1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)-1H-1,2,3-triazol-4-yl)methyl)-2-methyl-7-phenyl-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine-4(3H)-one 
• 1314535-14-2 3-((1-decyl-1H-1,2,3-triazol-4-yl)methyl)-2-methyl-7-phenyl-5-(trifluoromethyl)pyrido[2,3-d]pyrimidin-4(3H)-one 
• 1314535-15-3 2-methyl-7-phenyl-3-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)-5-(trifluoromethyl) pyrido[2,3-d]pyrimidin-4(3H)-one 
• 1314535-22-2 4-((1-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)-1H-1,2,3-triazol-4yl)methoxy)-2-methyl-7-phenyl-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine 
• 1314535-03-9 2-methyl-7-phenyl-4-(prop-2-ynyloxy)-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine 
• 1314534-95-6 2-methyl-7-phenyl-3-(prop-2-ynyl)-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine-4(3H)-one 

Relevant academic research and scientific papers

A simple one pot synthesis of novel tricyclic quinazolinones

Synthesis of a series of tricyclic quinazolinones have been accomplished starting from anthranilamide and 1,3-cyclic dione promoted by TsOH·H2O The protocol presented herein based on retro-Dieckmann type reaction, leading to incorporation of dione as an acyclic unit into the product. Simple reaction conditions, broad scope, excellent yields are the advantages of this protocol. Further, this methodology is extended to the synthesis of pyridopyrimidinones and benzimidazopyridines.

Synthesis of novel alkyltriazole tagged pyrido[2,3-d]pyrimidine derivatives and their anticancer activity

A series of novel alkyltriazole tagged pyrido[2,3-d]pyrimidine derivatives 5 and 6 was prepared starting from 2,3-active functional pyridine 1 via cyclization, propargylation followed by reaction with alkyl or perfluoroalkyl azides under Sharpless conditi