131470-23-0

Basic information

• Product Name: Benzenemethanol, 2-amino-a-ethenyl-
• CAS NO: 131470-23-0
• Molecular Formula: C9H11NO
• Molecular Weight: 149.192
• Mol File: 131470-23-0.mol

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 2-amino-a-ethenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 2-amino-a-ethenyl-(131470-23-0)
• EPA Substance Registry System: Benzenemethanol, 2-amino-a-ethenyl-(131470-23-0)

Safety Data

• Hazardous Substances Data: 131470-23-0(Hazardous Substances Data)

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 529-23-7 o-aminobenzaldehyde 
• 323579-94-8 1-(2-nitrophenyl)-2-propen-1-ol 

Downstream Products

• 612-58-8 3-methylquinoline 
• 54620-84-7 4,5-dihydro-3H-1-benzazepin-5-ol 

Relevant articles and documents

Exploring the Ring-Closing Metathesis for the Construction of the Solomonamide Macrocyclic Core: Identification of Bioactive Precursors

New synthetic strategies directed toward the novel cyclopeptides solomonamides have been explored utilizing an olefin metathesis as the key reaction. In the various strategies investigated, we worked on minimally oxidized systems, and the olefin metathesis reaction demonstrated efficiency and validity for the construction of the macrocyclic core. The described synthetic strategies toward the solomonamides are well suited for the subsequent access to the natural products and represent flexible and diversity-oriented routes that allow for the generation of a variety of analogues via oxidative transformations. In addition, preliminary biological evaluations of the generated solomonamide precursors revealed antitumor activity against various tumor cell lines.

AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR

The present invention provides a compound represented by the following formula (I): [wherein, A represents a group of the following formula (A-1): etc., R1 and R2 each independently represent a hydrogen atom etc., Z represents CR3 etc., W represents CR4 etc., Q represents CR5 etc., R3, R4 and R5 each independently represent a hydrogen atom etc., Y represents an oxygen atom or sulfur atom, X represents an oxygen atom etc. and B represents an optionally substituted aryl group or optionally substituted heteroaryl group], the prodrug thereof or the pharmaceutically acceptable salt thereof for preventing or treating various diseases such as hypertesion, cerebral stroke, cardiac failure, etc.

The Stereochemistry of Organometallic Compounds. XXXV. Hydroformylation of ortho-Propenylanilines and ortho-Propenylphenols: a New Route to 4,5-Dihydro-3H-1-benzazepines

Rhodium-catalyzed hydroformylation of readily available ortho-propenylanilines gives 4,5-dihydro-3H-1-benzazepines together with small amounts of substituted 3-methylquinolines (15percent).The regioselectivity of these reactions and the hydroformylation of related ortho-propenylphenols are discussed.