1314700-36-1

Basic information

• Product Name: 3-phenyl α,α-dimethylbenzylamine
• Synonyms: 3-phenyl α,α-dimethylbenzylamine
• CAS NO: 1314700-36-1
• Molecular Weight: 211.307
• Mol File: 1314700-36-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-phenyl α,α-dimethylbenzylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyl α,α-dimethylbenzylamine(1314700-36-1)
• EPA Substance Registry System: 3-phenyl α,α-dimethylbenzylamine(1314700-36-1)

Safety Data

• Hazardous Substances Data: 1314700-36-1(Hazardous Substances Data)

Upstream product

• 3112-01-4 3-phenylacetophenone 
• 69261-39-8 2-(4-biphenylyl)-2-propanol 
• 24973-50-0 3-phenylbenzonitrile 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 1245750-45-1 C₂₃H₂₂ClN₃O₂ 
• 1397293-27-4 4-nitrophenyl (2-([1,1'-biphenyl]-3-yl)propan-2-yl)carbamate 

Relevant articles and documents

One-Pot C-H Arylation/Lactamization Cascade Reaction of Free Benzylamines

An efficient method has been developed for the synthesis of seven-membered biaryl lactams involving Pd-catalyzed, native amine-directed, ortho-arylation of benzylamines followed by in situ lactamization. This cascade sequence is enabled by the use of 2-iodobenzoates, which facilitates C-H arylation from the free amine under conditions that typically require an improved directing group approach. This reaction is characterized by a broad substrate scope with good functional group tolerance. The need for an ester versus carboxylic acid-functionalized coupling partner is also explored, as is the potential for synthesizing eight-membered biaryl lactams. Various applications are also investigated, including access to the aza-brassinolide core.