1314716-36-3Relevant academic research and scientific papers
Diastereoselective synthesis of macrocycles incorporating the spiro-indolofurans and -indolodioxolanes
Muthusamy, Sengodagounder,Karikalan, Thangaraju
, p. 1443 - 1451 (2012)
Generation of intramolecular macrocyclic carbonyl ylides from aldehyde group tethered to diazoamides in the presence of rhodium(II) acetate and their successful [3+2]-cycloaddition afforded the corresponding macrocycles incorporating spiro-indolofurans, -indolofuropyrroles, -indolofurofurans, and -indolodioxolanes in moderate to good yield with complete diastereoselectivity. The competition between the electrocyclization and [3+2]-cycloaddition reactions of macrocyclic carbonyl ylides was also demonstrated.
