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2-Buten-1-one, 3-amino-1-(4-methylphenyl)-, also known as 3-amino-1-(p-tolyl)-2-butanone, is an organic compound with the chemical formula C11H15NO. It is a derivative of 2-butanone, featuring an amino group at the 3-position and a 4-methylphenyl group at the 1-position. 2-Buten-1-one, 3-amino-1-(4-methylphenyl)- is a colorless to pale yellow liquid with a molecular weight of 175.24 g/mol. It is used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. Due to its reactivity, it is important to handle this chemical with care, following proper safety protocols.

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  • 131474-81-2 Structure
  • Basic information

    1. Product Name: 2-Buten-1-one, 3-amino-1-(4-methylphenyl)-
    2. Synonyms:
    3. CAS NO:131474-81-2
    4. Molecular Formula: C11H13NO
    5. Molecular Weight: 175.23
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 131474-81-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-Buten-1-one, 3-amino-1-(4-methylphenyl)-(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-Buten-1-one, 3-amino-1-(4-methylphenyl)-(131474-81-2)
    11. EPA Substance Registry System: 2-Buten-1-one, 3-amino-1-(4-methylphenyl)-(131474-81-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 131474-81-2(Hazardous Substances Data)

131474-81-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 131474-81-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,4,7 and 4 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 131474-81:
(8*1)+(7*3)+(6*1)+(5*4)+(4*7)+(3*4)+(2*8)+(1*1)=112
112 % 10 = 2
So 131474-81-2 is a valid CAS Registry Number.

131474-81-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-amino-1-(4-methylphenyl)but-2-en-1-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:131474-81-2 SDS

131474-81-2Relevant articles and documents

Metal-Free Cascade Annulation Approach for Modular Assembly of Alkynyl/Benzoyl Functionalized Quinolines

Tang, Qiang,Yuan, Meng,Duan, Jiahui,Xu, Keke,Li, Ruxue,Xie, Mengqing,Kong, Shuwen,He, Xinwei,Shang, Yongjia

supporting information, (2022/01/19)

A concise and efficient synthetic method for alkynyl quinolines through TfOH-promoted cascade 1,4-conjugate addition/intramolecular annulation/aromatization process is established. By virtue of reactive aza-o-AQM (in situ generated from modular propargylamine), this reaction proceeds smoothly to afford a variety of alkynyl quinolines in good to excellent yields. This transition-metal-free process features halogen groups tolerance, such as the ?Cl, ?Br, and ?I groups; thus, this protocol circumvents the inherent shortcomings of the existing Sonogashira coupling of halogenated quinolines.

Reactions of methyl ketones and (hetero)arylcarboxamides with N,N-dimethylacetamide dimethyl acetal. A simple metal-free synthesis of 2,4,6-trisubstituted pyridines

Prek, Benjamin,Groelj, Uro,Kasuni, Marta,Zupani, Silvo,Svete, Jurij,Stanovnik, Branko

, p. 184 - 195 (2015/02/19)

Two metal-free syntheses of 2,4,6-trisubstituted pyridines 10a-m and 16a-j are described. N,N,6-Trimethyl-4-(substituted)pyridin-2-amines 10 were prepared from aryl or heteroaryl methyl ketones which were transformed with N,N-dimethylacetamide dimethyl ac

4-Chromenonyl-1,4-dihydropyridines and their use

-

Page/Page column 31, (2010/02/17)

The present application relates to novel 4-chromenonyl-1,4-dihydropyridines, process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis o

NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE AT1 AND ETA RECEPTORS

-

Page/Page column 148, (2010/11/28)

The present invention relates to new compounds of the formula [Chemical formula should be inserted here. Please see paper copy] wherein R1, R2, R3, and R31 are as specified herein. The invention also relates to a method for preparation thereof, as well as combinations of the new compounds with previously known agents. The invention also relates to the use of the above-mentioned compounds and combinations for the preparation of a medicament for treating hypertension of different kinds, alleviating organ damage of different kinds, treating or preventing diabetic nephropathy, treating endothelin and angiotensin mediated disorders, and treating prostate cancer.

The use of K-10/ultrasound in the selective synthesis of unsymmetrical β-enamino ketones

Valduga, Claudete J.,Squizani, Adriana,Braibante, Hugo S.,Braibante, Mara E.F.

, p. 1019 - 1022 (2007/10/03)

p-Phenyl substituted β-enamino ketones 2a-p and cyclic β-enamino ketones 4, 6a-f have been prepared by a selective method by dispersing 1,3- diketones and amines on montmorillonite K-10 under sonication.

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