131474-81-2

Basic information

• Product Name: 2-Buten-1-one, 3-amino-1-(4-methylphenyl)-
• CAS NO: 131474-81-2
• Molecular Formula: C11H13NO
• Molecular Weight: 175.23
• Mol File: 131474-81-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Buten-1-one, 3-amino-1-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Buten-1-one, 3-amino-1-(4-methylphenyl)-(131474-81-2)
• EPA Substance Registry System: 2-Buten-1-one, 3-amino-1-(4-methylphenyl)-(131474-81-2)

Safety Data

• Hazardous Substances Data: 131474-81-2(Hazardous Substances Data)

Upstream product

• 112778-98-0 3-(dimethylamino)-1-(-4-methylphenyl)but-2-en-1-one 
• 122-00-9 para-methylacetophenone 
• 4023-79-4 1-(4-methylphenyl)butan-1,3-dione 
• 631-61-8 ammonium acetate 
• 4211-89-6 3-methyl-5-(4-methylphenyl)isoxazole 

Downstream Products

• 90861-52-2 1H-2-amino-4-toluoylpyrazole 
• 921622-61-9 Ethyl 2,6-dimethyl-5-(4-methylbenzoyl)-4-(2-methyl-4-oxo-4H-chromen-8-yl)-1,4-dihydro-pyridine-3-carboxylate 
• 921622-64-2 Propyl 2,6-dimethyl-5-(4-methylbenzoyl)-4-(2-methyl-4-oxo-4H-chromen-8-yl)-1,4-dihydro-pyridine-3-carboxylate 
• 921622-54-0 Methyl 2,6-dimethyl-5-(4-methylbenzoyl)-4-(2-methyl-4-oxo-4H-chromen-8-yl)-1,4-dihydro-pyridine-3-carboxylate 
• 948350-11-6 2,6-dimethyl-3-(4-methyl-benzoyl)-1H-pyridin-4-one 
• 131475-16-6 ethyl 5-methyl-3-p-tolyl-2-pyrrolecarboxylate 

Relevant articles and documents

Metal-Free Cascade Annulation Approach for Modular Assembly of Alkynyl/Benzoyl Functionalized Quinolines

A concise and efficient synthetic method for alkynyl quinolines through TfOH-promoted cascade 1,4-conjugate addition/intramolecular annulation/aromatization process is established. By virtue of reactive aza-o-AQM (in situ generated from modular propargylamine), this reaction proceeds smoothly to afford a variety of alkynyl quinolines in good to excellent yields. This transition-metal-free process features halogen groups tolerance, such as the ?Cl, ?Br, and ?I groups; thus, this protocol circumvents the inherent shortcomings of the existing Sonogashira coupling of halogenated quinolines.

4-Chromenonyl-1,4-dihydropyridines and their use

The present application relates to novel 4-chromenonyl-1,4-dihydropyridines, process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis o

The use of K-10/ultrasound in the selective synthesis of unsymmetrical β-enamino ketones

p-Phenyl substituted β-enamino ketones 2a-p and cyclic β-enamino ketones 4, 6a-f have been prepared by a selective method by dispersing 1,3- diketones and amines on montmorillonite K-10 under sonication.