1314779-48-0Relevant articles and documents
Copper-catalyzed trifluoromethylation of N,N-dialkylhydrazones
Pair, Etienne,Monteiro, Nuno,Bouyssi, Didier,Baudoin, Olivier
, p. 5346 - 5349 (2013)
Mild and practical: Trifluoromethylation of (hetero)aromatic aldehyde N,N-dialkylhydrazones was achieved at room temperature by using Togni's trifluoromethylation reagent under CuCl catalysis (see scheme). This simple reaction is believed to occur by a CF3-radical-transfer mechanism and yields useful trifluoromethylated building blocks. Copyright