131480-05-2Relevant academic research and scientific papers
Development of a straightforward and efficient protocol for the one-pot multicomponent synthesis of substituted alpha-aminoallylphosphonates under catalyst-free condition
Brahmachari, Goutam,Begam, Sanchari,Karmakar, Indrajit,Gupta, Vivek K
, p. 769 - 779 (2021)
A catalyst-free practical version of Kabachnik-Fields strategy has been developed for the efficient and straightforward one-pot synthesis of diversely substituted α-aminoallylphosphonates, a limitedly reported class of biologically important α-aminophosph
Synthesis of organophosphorus compounds via silyl esters of phosphorous acids
Afarinkia, Kamyar,Rees, Charles W.,Cadogan, John I. G.
, p. 7175 - 7196 (2007/10/02)
The addition of trimethylsilyloxy phosphorus (III)derivatives generated in situ to imines at room temperature provides a mild selective and high yielding route to α-aminoalkylphosphorate and α-aminoalkylphenylphosphinate esters. Isocyanates and carbodiimides react similarly to give phosphonoureas and phosphonoguarnidines respectively aldehydes and ketones are much less reactive and cyanides are inert.
