1314864-59-9

Basic information

• Product Name: S(+)-2-(2-ethylhexanamido)benzamide
• Synonyms: S(+)-2-(2-ethylhexanamido)benzamide
• CAS NO: 1314864-59-9
• Molecular Weight: 262.352
• Mol File: 1314864-59-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: S(+)-2-(2-ethylhexanamido)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: S(+)-2-(2-ethylhexanamido)benzamide(1314864-59-9)
• EPA Substance Registry System: S(+)-2-(2-ethylhexanamido)benzamide(1314864-59-9)

Safety Data

• Hazardous Substances Data: 1314864-59-9(Hazardous Substances Data)

Upstream product

• 72377-05-0 (2S)-ethylhexanoic acid 
• 149-57-5 2-Ethylhexanoic acid 
• 760-67-8 (2S)-ethylhexanoyl chloride 
• 28144-70-9 anthranilic acid amide 
• 93344-33-3 (S)ethyl-2-hexanoic acid (R)phenyl-1-ethylamine salt 

Relevant articles and documents

Antifungal quinazolinones from marine-derived Bacillus cereus and their preparation

Two new quinazolinones alkaloids, R(+)-2-(heptan-3-yl)quinazolin-4(3H)-one (1) and (2R,3′R)+(2S,3′R)-2-(heptan-3-yl)-2,3-dihydroquinazolin- 4(1H)-one (2) (a pair of epimers), as well as seven known analogues, 2-methylquinazolin-4(3H)-one (3), 2-benzylquinazolin-4(3H)-one (4), cyclo-(Pro-Ile), cyclo-(Pro-Leu), cyclo-(Pro-Val), cyclo-(Pro-Phe), and cyclo-(Tyr-Pro) were isolated from the n-butyl alcohol extract of the marine-derived bacterium Bacillus cereus 041381. The new compounds were identified by spectroscopic analysis and chemical synthesis. Four optical isomers 5-8 were also synthesized. Compounds 1-8 all showed moderate antifungal activity against Candida albicans with MIC values of 1.3-15.6 μM. Compound 5 exhibits the most powerful antifungal activity, which may reveal that S-configuration and 2,3-double bond were necessary for antifungal activity, and the racemization at C-2 and C-3′ reduced the antifungal activity.