131497-05-7Relevant academic research and scientific papers
Rotational barriers in N,N-diethylbenzamides: Substituent and solvent effects
Turnbull, Mark M.,Nelson, Donald J.,Lekouses, Wendy,Sarnov, Mark L.,Tartarini, Kimberly A.,Huang, Tie-Kang
, p. 6613 - 6622 (1990)
The barrier to rotation about the C-N bond In a series of substituted N,N-diethylbenzamides has been calculated via total bandshape analysis of the exchanging alkyl carbons in the 13C-NMR spectra in four solvents: C6D6, CD
A practical in situ generation of the schwartz reagent. reduction of tertiary amides to aldehydes and hydrozirconation
Zhao, Yigang,Snieckus, Victor
supporting information, p. 390 - 393 (2014/04/03)
A new, highly efficient in situ protocol (Cp2ZrCl2/LiAlH(OBu-t)3) is described for the generation of the Schwartz reagent which provides a convenient method for the amide to aldehyde reduction and the regioselective hydrozirconation-iodination of alkynes and alkenes. Highlighted are chemoselective reductions of benzamides derived by directed ortho metalation (DoM) chemistry, allowing the synthesis of valuable 1,2,3-substituted benzaldehydes. The single-step, three-component process proceeds in a very short reaction time, shows excellent functional group compatibility, and uses inexpensive and long-storage stable reducing reagents.
Method for Preparing Halogenated Amines
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Page/Page column 16-17, (2008/12/07)
This invention relates to methods for preparing halogenated amines.
