13150-00-0

Usage

Uses

Used in Detergency Industry:
Sodium 2-[2-[2-(dodecyloxy)ethoxy]ethoxy]ethyl sulphate is used as a surfactant for its ability to remove dirt and grease effectively. Its water-soluble properties and adherence to surfaces make it a valuable component in various cleaning products.
Used in Cleaning Products:
Sodium 2-[2-[2-(dodecyloxy)ethoxy]ethoxy]ethyl sulphate is used as a cleaning agent for its ability to break down and remove dirt and grease from surfaces. Its effectiveness in cleaning is attributed to its sulphate group and the dodecyloxy group, which enhance its cleansing capability.

InChI:InChI=1/C18H38O7S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-22-13-14-23-15-16-24-17-18-25-26(19,20)21;/h2-18H2,1H3,(H,19,20,21);/q;+1/p-1

Synthetic route

1-dodecyl alcohol (112-53-8) + C6H12O6S → Natrium-(α-dodecyl-ω-sulfatotrioxyethylen) (13150-00-0)

Conditions	Yield
Stage #1: 1-dodecyl alcohol With sodium hydride In tetrahydrofuran at 0 - 20℃; for 0.25h; Stage #2: C6H12O6S In tetrahydrofuran at 20℃; for 3h;	77%

2-[2-(2-Dodecyloxy-ethoxy)-ethoxy]-ethanol (3055-94-5) → Natrium-(α-dodecyl-ω-sulfatotrioxyethylen) (13150-00-0)

Conditions	Yield
Stage #1: 2-[2-(2-Dodecyloxy-ethoxy)-ethoxy]-ethanol With sulfur trioxide at 27 - 125℃; Industry scale; Stage #2: With sodium hydroxide; sodium carbonate In water Product distribution / selectivity; Industry scale;
Stage #1: 2-[2-(2-Dodecyloxy-ethoxy)-ethoxy]-ethanol With chlorosulfonic acid at 25 - 30℃; for 0.5h; Stage #2: With sodium hydroxide In water

diethylene glycol monododecyl ether (3055-93-4) + diethylene glycol monotetradecyl ether (56049-79-7) → Natrium-(α-dodecyl-ω-sulfatotrioxyethylen) (13150-00-0) + sodium dodecyl diethoxy sulfate (3088-31-1)

Conditions	Yield
Stage #1: diethylene glycol monododecyl ether; diethylene glycol monotetradecyl ether With sulfur trioxide at 35 - 65℃; Industry scale; Stage #2: With sodium hydroxide; sodium carbonate In water Product distribution / selectivity; Industry scale;

2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → Natrium-(α-dodecyl-ω-sulfatotrioxyethylen) (13150-00-0)

Conditions	Yield
Multi-step reaction with 2 steps 1.1: triethylamine; thionyl chloride / dichloromethane / 1 h 1.2: 0 - 20 °C 1.3: 2 h / 0 - 20 °C 2.1: sodium hydride / tetrahydrofuran / 0.25 h / 0 - 20 °C 2.2: 3 h / 20 °C View Scheme

Upstream product

• 3055-94-5 2-[2-(2-Dodecyloxy-ethoxy)-ethoxy]-ethanol 
• 3055-93-4 diethylene glycol monododecyl ether 
• 56049-79-7 diethylene glycol monotetradecyl ether 
• 112-53-8 1-dodecyl alcohol 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 

Relevant academic research and scientific papers

Synthesis and surface properties of N,N-dimethyl-N-dodecyl polyoxyethylene amine-based surfactants: Amine oxide, betaine and sulfobetaine

Nonionic-zwitterionic hybrid surfactants, namely N,N-dimethyl-N-dodecyl polyoxyethylene (3) amine oxide, and the corresponding betaine and/or sulfobetaine, have been synthesized. Their molecule structures were characterized by means of electrospray ionization mass spectrometry and 1H nuclear magnetic resonance. Compared to the structurally related conventional amine oxide, betaine and sulfobetaine, the critical micelle concentrations of the three hybrid surfactants are one order of magnitude smaller than those of traditional ones. The polyoxyethylene segment between the hydrophilic head group and the hydrophobic tail makes the surface activities of the hybrid surfactants superior to their structure-related counterparts.

Preparation method and application of monodisperse nonapolyethylene glycol dodecyl alcohol monoether and sulphate thereof

The invention discloses a preparation method and application of monodisperse nonapolyethylene glycol dodecyl alcohol monoether and sulphate thereof and belongs to the field of pharmaceutical and chemical industry. Starting from dodecyl alcohol, firstly ring-opening reaction is carried out with nonapolyethylene glycol cyclic sulphate once or with multiple oligomeric ethylene glycol cyclic sulphate containing nine ethylene glycol units in total for multiple times in presence of alkali, so that sulphate of nonapolyethylene glycol dodecyl alcohol monoether is obtained; and then hydrolysis is carried out in presence of sulphuric acid, so that the nonapolyethylene glycol dodecyl alcohol monoether is obtained. The preparation method can be applied to preparation of long-chain alkyl monoether of monodisperse polyethylene glycol and sulphate thereof. The preparation method disclosed by the invention has the advantages that single molecular weight polyethylene glycol cyclic sulphate is taken as a raw material, efficient synthesis of more than hexameric alkyl alcohol monoether of ethylene glycol is realized, no protecting group is used during synthesis, steps are simple and convenient, the preparation method is applicable to industrial production, and the obtained product has obvious advantages compared with existing prepared lauromacrogol.

Method and Device for the Sulfonation or Sulfation of Sulfonatable or Sulfatable Organic Substances and for Performing Faster, Strongly Exothermic Gas/Liquid Reactions

A method and a device for the sulfonation or the sulfation of organic liquid raw materials with an S03/air mixture and other reaction gases in order to perform rapid, highly exothermic gas-liquid reactions in conventional thin-layer falling-film reactors are disclosed. The introduction of the S03/air mixture occurs through several feed locations, which are located within (along) the reaction tube or reaction tubes or in the annular gap of annular-gap falling-film reactors. High peak temperatures, undesirable byproducts, worsening of the color and local oversulfation or oversulfonation, which leads to side reactions, are largely avoided.