131529-83-4

Upstream product

• 134025-20-0 N-Methyl-1,5-diphenylpent-4-enylamine 
• 4392-24-9 Cinnamyl bromide 
• 28748-27-8 ethyl 2-benzoyl-5-phenyl-pent-4-enoate 
• 28069-36-5 1,5-diphenyl-4-penten-1-one 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 
• 131529-77-6 N-Methyl-1,5-diphenyl-4-pentynylamine 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 93321-18-7 1,5-diphenyl-4-pentyn-1-one 
• 131529-79-8 (E)-2-Benzylidene-1-methyl-5-phenylpyrrolidine 
• 134025-20-0 N-Methyl-1,5-diphenylpent-4-enylamine 

Relevant academic research and scientific papers

New anionic cyclization of 4- and 5-alkynylamines: Synthesis of 2-Benzylidene pyrrolidines and piperidines

Treatment of 4- and 5-alkynylamines with 0.5-1.2 equiv. of butyllithium brought about a facile anionic cyclization, giving the corresponding enamine pyrrolidines and piperidines having an exo double bond in high yields. Treatment of 4-alkynamides with lit

Stereoselective cyclization of δ-alkenylamines catalyzed with butyllithium. Synthesis of cis-N-methyl-2,5-disubstituted pyrrolidines

Treatment of δ-alkenylamines (1a-1d) with a catalytic amount of butyllithium gave cis-N-methyl-2,5-disubstituted pyrrolidines (2a-2d) stereo selectively in good yields.

Stereoselective synthesis of 4- or 5-substituted 2-benzyl- and 2-benzoylpyrrolidines by means of anodic oxidation of δ-alkenylamines

The anodic oxidation of the lithium amides of δ-alkenylamines 6a, 6b, 6c, 10a, and 10b gave stereoselectively cis-5-substituted 2-benzyl-1-methylpyrrolidines (7a, 7b, 7c) and 4-substituted 2-benzyl-1-methyl-pyrrolidines (11a, 11b) in high yields. The anod

NEW FACILE SYNTHESIS OF SUBSTITUTED 2-BENZYLIDENEPYRROLIDINES BY THE ANIONIC CYCLIZATION OF δ-ALKYNYLAMINES

Treatment of δ-alkynylamines with butyllithium or lithium aluminum hydride brought about a facile anionic cyclization, giving high yields of the corresponding enamine pyrrolidines having an exo double bound.