131533-35-2Relevant academic research and scientific papers
Formation of 3-azetidin-2-ones: Stereocontrolled Formal Approach to (+/-)-Thienamycin and (+/-)-β-(Hydroxyalkyl)aspartic Acid Derivatives
Palomo, Claudio,Aizpurua, Jesus M.,Urchegui, Raquel,Iturburu, Miren
, p. 1571 - 1579 (2007/10/02)
Reaction between (+/-)-β-(dimethylphenylsilyl)alkanoyl chlorides and imines of glyoxylic esters provided a route to (+/-)-cis-3--4-alkoxycarbonyl β-lactams, while addition of the Fleming's silylcuprate reagent to methyl crot
Preparation of 3-Alkyl β-Lactams via the Ketene-Imine Cycloaddition Reaction Using α-(Phenylthio)alkanoyl Halides as Starting Materials:Application to the Synthesis of (+/-)-Carbapenem Building Blocks and Related Compounds
Palomo, Claudio,Cossio, Fernando P.,Odiozola, Jose M.,Oiarbide, Mikel,Ontoria, Jesus M.
, p. 4418 - 4428 (2007/10/02)
Preparation of appropriately substituted 3-alkyl β-lactams via the ketene (or equivalent)-imine cycloaddition reaction is described.The dehydrochlorination reaction of α-(phenylthio)alkanoyl chlorides with triethylamine in the presence of imines derived f
β-Lactams via α,β-Unsaturated Acid Chlorides: Intermediates for Carbapenem Antibiotics
Manhas, M. S.,Ghosh, Malay,Bose, Ajay K.
, p. 575 - 580 (2007/10/02)
Stereocontrolled synthesis of α-vinyl β-lactams and their transformation to convenient intermediates for PS-5, PS-6, asparenomycin, and thienamycin are described.
