131544-89-3Relevant academic research and scientific papers
Synthesis and chiral separation of some antitumor agents
Singh, Satendra,Meyer, Karen L.,Magarian, Robert A.
, p. 81 - 94 (2007/10/03)
Four Z-isomers of 1,1-dichloro-2,2,3-triarylcyclopropane (DTACs), designed as potent antitumor agents, were synthesized from their appropriately substituted ethenes, which were prepared from the Grignard reaction followed by the dehydration of their inter
Synthesis and Biological Evaluation of a Series of 1,1-Dichloro-2,2,3-triarylcyclopropanes as Pure Antiestrogens
Day, Billy W.,Magarian, Robert A.,Jain, Pramod T.,Pento, J. Thomas,Mousissian, Gorgin K.,Meyer, Karen L.
, p. 842 - 851 (2007/10/02)
A series of 1,1,-dichloro-2,2,3-triarylcyclopropanes (DTACs) was synthesized and evaluated as pure antiestrogens.Addition of 4-methoxy- or 4-(benzyloxy)phenyl Grignard reagents to p-methoxy, p-benzyloxy, or unsubstituted deoxybenzoins, followed by dehydra
