1315494-53-1Relevant articles and documents
Kilogram-scale asymmetric ruthenium-catalyzed hydrogenation of a tetrasubstituted fluoroenamide
Stumpf, Andreas,Reynolds, Mark,Sutherlin, Daniel,Babu, Srinivasan,Bappert, Erhard,Spindler, Felix,Welch, Michael,Gaudino, John
, p. 3367 - 3372 (2012/03/10)
Ruthenium-catalyzed asymmetric homogeneous hydrogenation (AHH) is used as the key step of a multi-kilogram scale synthesis of an enantiomeric fluoropiperidine. The AHH of a tetrasubstituted β-fluoroenamide is carried out under mild conditions using a Ru/J