13155-42-5

Upstream product

• 1676-73-9 L-glutamic acid γ-benzyl ester 
• 7669-54-7 2-nitrobenzenesulfenyl chloride 

Downstream Products

• 60654-75-3 Nps-4-Lys(Boc)-NH-NH-Z 
• 60654-71-9 Nps-2-Lys(Boc)-NH-NH-Z 
• 60654-73-1 Nps-3-Lys(Boc)-NH-NH-Z 
• 50540-54-0 o-NPS-L-Glu(γ-Bzl)-OTcp(2,4,5) 
• 35971-38-1 Nps-Glu(OBzl)-OPcp 
• 5879-10-7 γ-Benzyl-α-(2-methylmercapto-ethyl)-L-glutamat 
• 47510-24-7 L-glutamic acid-5-benzyl ester-1-(4-nitro-phenyl ester) 
• 47846-47-9 Nps-Glu(OBzl)-Glu(OBzl)-OH 
• 19402-06-3 γ-Benzyl-L-glutaminsaeurepentachlorphenylester 
• 16876-92-9 α-<2-Nitrophenylsulfenyl>-γ-benzyl-L-glutaminsaeure-4-nitrophenylester 
• 53236-81-0 H-glu(OBzl)-OPhCl₃(2,4,5) 

Relevant academic research and scientific papers

SYNTHESIS OF REGULAR POLYPEPTIDES INCLUDING POLYFUNCTIONAL AMINO ACIDS

Polypeptides of regular structure with the sequences His-Glu, Ser-Glu, Try-Glu, His-Tyr, and Glu-His have been synthesized by the 2,4,5-trichlorophenyl ester method.Polymerization was carried out in dimethyl sulfoxide and dimethylformamide.The polymers were purified by dialysis against water.In the process of synthesizing the monomers, the α-amino groups of the acids were protected by ortho-nitrophenylsulfenyl (o-NPS-), benzyloxycarbonyl (Z-), and tert-butoxycarbonyl (t-BOC-) groups.The imidazole group of histidine was Z-protected, and the γ-hydroxy group of glutamic acid and the phenolic OH group of tyrosine were benzyl-protected (Bzl-).