1315570-92-3

Upstream product

• 1315570-82-1 C₂₁H₁₉NO₅S 
• 109-77-3 malononitrile 

Relevant academic research and scientific papers

Expeditious assembly of a 2-Amino-4H-chromene skeleton by using an enantioselective Mannich intramolecular ring cyclization-tautomerization cascade sequence

Easy to assemble! An enantioselective cascade Mannich intramolecular ring cyclization-tautomerization reaction of malononitrile with 2-hydroxyl N-protected α-amido sulfone is described (see scheme), which provides a new route to the synthesis of the privi

Enantioselective organocatalytic synthesis of medicinally privileged 2-amino-4H-chromene-3-carbonitriles via a cascade process

An efficient organocatalytic cascade approach toward medicinally privileged 2-amino-4H-chromene-3-carbonitriles is reported. The enantioselective synthesis of these compounds is achieved in high yields and good to high ee values (up to 96% yield and 89% e