131575-57-0

Upstream product

• 131575-44-5 4-(2,4-Dimethoxy-phenyl)-3-hydroxy-chromen-2-one 
• 36896-61-4 2,4-dimethoxyphenyllead triacetate 
• 939-19-5 3-Hydroxy-cumarin 
• 17831-88-8 4-chloro-2H-1-benzopyran-2-one 
• 133730-34-4 2,4-dimethoxyphenylboronic acid 
• 131575-52-5 Trifluoro-methanesulfonic acid 4-(2,4-dimethoxy-phenyl)-2-oxo-2H-chromen-3-yl ester 

Relevant academic research and scientific papers

Synthesis of neoflavones by Suzuki arylation of 4-substituted coumarins

Palladium-catalysed coupling of the 4-chloro- or 4-bromo-coumarins 1-4 with arylboronic acids 5-13 under the Suzuki reaction conditions constitutes an efficient access to 4-arylcoumarins. These 4-arylcoumarins can also be obtained in good yields (70-97%)

A New Approach to Neoflavonoid Synthesis

Neoflavonoids or 4-arylcoumarins are prepared by arylation of 3-hydroxycoumarins with aryl-lead triacetates followed by palladium-catalysed reduction of the derived 3-trifluoromethylsulphonyloxyarylcoumarins.