131589-91-8

Upstream product

• 6748-85-2 methyl 2,3-di-O-benzoyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 97-30-3 methyl-alpha-D-glucopyranoside 
• 131589-94-1 methyl 2,3-di-O-benzoyl-4-O-benzyl-6-deoxy-α-D-glucopyranoside 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 3162-96-7 methyl 4,6-O-benzylidene-α-D-glucopyranoside 
• 131589-92-9 methyl 4-O-benzyl-6-deoxy-α-D-glucopyranoside 
• 106711-52-8 Acetic acid (2R,3R,4S,5R,6R)-5-acetoxy-4-benzyloxy-2-bromo-6-methyl-tetrahydro-pyran-3-yl ester 
• 106711-52-8 Acetic acid (2R,3R,4S,5R,6R)-5-acetoxy-4-benzyloxy-2-bromo-6-methyl-tetrahydro-pyran-3-yl ester 
• 89539-31-1 methyl 2,3-di-O-benzoyl-4-O-benzyl-α-D-glucopyranoside 
• 131589-93-0 methyl 2,3-di-O-benzoyl-4-O-benzyl-6-bromo-6-deoxy-α-D-glucopyranoside 

Downstream Products

• 131589-95-2 methyl 4-O-benzyl-6-deoxy-2-O-(3-O-benzyl-6-deoxy-β-D-glucopyranosyl)-α-D-glucopyranoside 
• 114828-00-1 methyl 3-O-(chloroacetyl)-4-O-benzyl-6-deoxy-2-O-(2,4-bis-O-(chloroacetyl)-3-O-benzyl-6-deoxy-β-D-glucopyranosyl)-α-D-glucopyranoside 

Relevant academic research and scientific papers

Phyllanthoside-Phyllanthostatin Synthetic Studies. 9. Total Syntheses of (-)-Phyllanthostatin 1, (+)-Phyllanthostatin 2, and (+)-Phyllanthostatin 3

Phyllanthostatins 1, 2, and 3 (2-4) have been synthesized for the first time. The unusual 1′→2β glycosidic linkages of the disaccharide moieties were constructed via anchimerically-assisted Koenigs-Knorr reactions. The novel β-glycosyl esters were then ge

The Total Synthesis of (-)-Phyllanthostatin-1

The first total synthesis of the important antitumor glycoside (-)-phyllanthostatin-1 (1) is described; the key steps include a regioselective Koenigs-Knorr reaction to establish the 1,2-O-linkage in disaccharide (6) and a stereoselective triphenylphosphine-di-isopropyl azodicarboxylate (TPP-DIAD) glycosidation of hemiacetal (12) with aglycone (15).