131589-92-9

Upstream product

• 131589-94-1 methyl 2,3-di-O-benzoyl-4-O-benzyl-6-deoxy-α-D-glucopyranoside 
• 131589-93-0 methyl 2,3-di-O-benzoyl-4-O-benzyl-6-bromo-6-deoxy-α-D-glucopyranoside 
• 3162-96-7 methyl 4,6-O-benzylidene-α-D-glucopyranoside 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 3162-96-7 4,6-O-benzylidene-1-O-methyl-α-D-glucopyranoside 
• 6748-85-2 methyl 2,3-di-O-benzoyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 97-30-3 methyl-alpha-D-glucopyranoside 
• 89539-31-1 methyl 2,3-di-O-benzoyl-4-O-benzyl-α-D-glucopyranoside 

Downstream Products

• 109923-11-7 methyl 4-O-benzyl-6-deoxy-2,3-di-O-p-tolylsulfonyl-α-D-glucopyranoside 
• 1415663-21-6 methyl 2-O-benzoyl-4-O-benzyl-3,6-dideoxy-3-dimethylamino-α-D-glucopyranoside 
• 1415663-22-7 1-O-acetyl-2-O-benzoyl-4-O-benzyl-3,6-dideoxy-3-dimethylamino-D-glucopyranose 
• 1415663-36-3 2-O-benzoyl-4-O-benzyl-3,6-dideoxy-3-dimethylamino-β-D-glucopyranosyl fluoride 
• 1415663-29-4 2-O-benzoyl-4-O-benzyl-3,6-dideoxy-3-dimethylamino-α-D-glucopyranosyl fluoride 
• 1415663-24-9 p-methylphenyl 2-O-benzoyl-4-O-benzyl-3,6-dideoxy-3-dimethylamino-1-thio-β-D-glucopyranoside 
• 1415663-25-0 C₂₂H₂₇NO₄S 
• 1415663-26-1 ethyl 2-O-benzoyl-3,6-dideoxy-3-dimethylamino-1-thio-β-D-glucopyranoside 
• 1415663-27-2 C₁₇H₂₅NO₄S 
• 1415663-28-3 2-O-benzoyl-4-O-benzyl-3,6-dideoxy-3-dimethylamino-α-D-glucopyranosyl trichloroacetimidate 
• 1415663-30-7 5-(2-O-benzoyl-4-O-benzyl-mycaminosyl)-3-O-descladinosyl-6-O-methyl-3-oxo-erythronolide A 11,12-cyclic carbonate 
• 1415663-31-8 5-(4-O-benzyl-mycaminosyl)-3-O-descladinosyl-6-O-methyl-3-oxo-erythronolide A?11,12-cyclic carbonate 
• 114828-00-1 methyl 3-O-(chloroacetyl)-4-O-benzyl-6-deoxy-2-O-(2,4-bis-O-(chloroacetyl)-3-O-benzyl-6-deoxy-β-D-glucopyranosyl)-α-D-glucopyranoside 
• 131589-95-2 methyl 4-O-benzyl-6-deoxy-2-O-(3-O-benzyl-6-deoxy-β-D-glucopyranosyl)-α-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis and antibacterial activity of novel modified 5-O-desosamine ketolides

A series of novel modified 5-O-desosamine-ketolides were synthesized. The 5-O-desosamine fragment was removed from ketolide by an efficient and mild manipulation. 4-O-substituted desosamine was introduced into the ketolide aglycon and various coupling methods were essayed for the glycosylation. Three novel ketolides were tested for in vitro antibacterial activity against a panel of susceptible and resistant pathogens. Compound 26 showed potent activity against all the methicillin-sensitivity and resistant pathogens.

Phyllanthoside-Phyllanthostatin Synthetic Studies. 9. Total Syntheses of (-)-Phyllanthostatin 1, (+)-Phyllanthostatin 2, and (+)-Phyllanthostatin 3

Phyllanthostatins 1, 2, and 3 (2-4) have been synthesized for the first time. The unusual 1′→2β glycosidic linkages of the disaccharide moieties were constructed via anchimerically-assisted Koenigs-Knorr reactions. The novel β-glycosyl esters were then ge

The Total Synthesis of (-)-Phyllanthostatin-1

The first total synthesis of the important antitumor glycoside (-)-phyllanthostatin-1 (1) is described; the key steps include a regioselective Koenigs-Knorr reaction to establish the 1,2-O-linkage in disaccharide (6) and a stereoselective triphenylphosphine-di-isopropyl azodicarboxylate (TPP-DIAD) glycosidation of hemiacetal (12) with aglycone (15).