1415663-30-7

Basic information

• Product Name: 5-(2-O-benzoyl-4-O-benzyl-mycaminosyl)-3-O-descladinosyl-6-O-methyl-3-oxo-erythronolide A 11,12-cyclic carbonate
• Synonyms: 5-(2-O-benzoyl-4-O-benzyl-mycaminosyl)-3-O-descladinosyl-6-O-methyl-3-oxo-erythronolide A 11,12-cyclic carbonate
• CAS NO: 1415663-30-7
• Molecular Weight: 823.978
• Mol File: 1415663-30-7.mol

Chemical Properties

• CAS DataBase Reference: 5-(2-O-benzoyl-4-O-benzyl-mycaminosyl)-3-O-descladinosyl-6-O-methyl-3-oxo-erythronolide A 11,12-cyclic carbonate(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-O-benzoyl-4-O-benzyl-mycaminosyl)-3-O-descladinosyl-6-O-methyl-3-oxo-erythronolide A 11,12-cyclic carbonate(1415663-30-7)
• EPA Substance Registry System: 5-(2-O-benzoyl-4-O-benzyl-mycaminosyl)-3-O-descladinosyl-6-O-methyl-3-oxo-erythronolide A 11,12-cyclic carbonate(1415663-30-7)

Safety Data

• Hazardous Substances Data: 1415663-30-7(Hazardous Substances Data)

Upstream product

• 6748-85-2 methyl 2,3-di-O-benzoyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 3162-96-7 4,6-O-benzylidene-1-O-methyl-α-D-glucopyranoside 
• 97-30-3 methyl-alpha-D-glucopyranoside 
• 1415663-19-2 11,12-carbonate-11,12-dideoxy-5-hydroxyl-3-oxo-6-O-methyl-erythronolide A 
• 100-39-0 benzyl bromide 
• 143353-27-9 11,12-carbonate-11,12-dideoxy-3-O-descladinosyl-3-oxo-6-O-methyl-erythromycin A 
• 1415663-28-3 2-O-benzoyl-4-O-benzyl-3,6-dideoxy-3-dimethylamino-α-D-glucopyranosyl trichloroacetimidate 
• 1415663-27-2 C₁₇H₂₅NO₄S 
• 1415663-26-1 ethyl 2-O-benzoyl-3,6-dideoxy-3-dimethylamino-1-thio-β-D-glucopyranoside 
• 1415663-25-0 C₂₂H₂₇NO₄S 
• 1415663-24-9 p-methylphenyl 2-O-benzoyl-4-O-benzyl-3,6-dideoxy-3-dimethylamino-1-thio-β-D-glucopyranoside 
• 1415663-22-7 1-O-acetyl-2-O-benzoyl-4-O-benzyl-3,6-dideoxy-3-dimethylamino-D-glucopyranose 
• 1415663-21-6 methyl 2-O-benzoyl-4-O-benzyl-3,6-dideoxy-3-dimethylamino-α-D-glucopyranoside 
• 109923-12-8 methyl 2,3-anhydro-4-O-benzyl-6-deoxy-α-D-allopyranoside 

Downstream Products

• 1415663-31-8 5-(4-O-benzyl-mycaminosyl)-3-O-descladinosyl-6-O-methyl-3-oxo-erythronolide A?11,12-cyclic carbonate 

Relevant articles and documents

Synthesis and antibacterial activity of novel modified 5-O-desosamine ketolides

A series of novel modified 5-O-desosamine-ketolides were synthesized. The 5-O-desosamine fragment was removed from ketolide by an efficient and mild manipulation. 4-O-substituted desosamine was introduced into the ketolide aglycon and various coupling methods were essayed for the glycosylation. Three novel ketolides were tested for in vitro antibacterial activity against a panel of susceptible and resistant pathogens. Compound 26 showed potent activity against all the methicillin-sensitivity and resistant pathogens.