131606-87-6

Upstream product

• 131606-85-4 (R)-3-octadec-3-yne-1,2-diol 
• 22566-56-9 ethyl 2-oxooctadec-3-ynoate 
• 629-74-3 hexadec-1-yne 
• 1352742-30-3 (2R)-ethyl 2-hydroxyoctadec-3-ynoate 
• 131606-83-2 (R)-1,2-cyclohexylidenedioxyoctadec-3-yne 

Downstream Products

• 131606-89-8 (2R,3E)-1-trityloxyoctadec-3-en-2-ol 
• 156199-15-4 (2R,3S,2'R,3'E)-N-(2'-tert-butyldiphenylsilyloxy-3'-octadecenoyl)-1,3-isopropylidenedioxy-2-aminooctadecane 
• 1352742-33-6 (2R,3S,2'R,3'E)-N-(2'-tert-butyldiphenylsilyloxy-3'-octadecenoyl)-2-aminooctadecane-1,3-diol 
• 1352742-39-2 (2R,3R,2'R,3'E)-N-(2'-tert-butyldiphenylsilyloxy-3'-octadecenoyl)-1,3-isopropylidenedioxy-2-aminooctadecane 
• 1352742-40-5 (2S,3S,2'R,3'E)-N-(2'-tert-butyldiphenylsilyloxy-3'-octadecenoyl)-1,3-isopropylidenedioxy-2-aminooctadecane 
• 1352742-41-6 (2R,3R,2'R,3'E)-N-(2'-tert-butyldiphenylsilyloxy-3'-octadecenoyl)-2-aminooctadecane-1,3-diol 
• 1352742-42-7 (2S,3S,2'R,3'E)-N-(2'-tert-butyldiphenylsilyloxy-3'-octadecenoyl)-2-aminooctadecane-1,3-diol 
• 156159-44-3 (2S,2'R,3R,3'E)-N-(2'-t-butyldiphenylsilyloxy-3'-octadecenoyl)-1,3-O-isopropyliden-<2-amino-1,3-dihydroxyoctadecane> 
• 156159-40-9 (2R,3E)-2-tert-butyldiphenylsilyloxy-3-octadecen-1-ol 
• 156159-42-1 (2R,3E)-2-(tert-Butyldiphenylsilyloxy)-3-octadecanoic acid 
• 156159-39-6 (2R,3E)-1-tert-butyldimethylsilyloxy-2-tert-butyldiphenylsilyloxy-3-octadecene 
• 156257-69-1 (2S,2'R,3R,3'E)-N-(2'-t-butyldiphenylsilyloxy-3'-octadecenoyl)-<2-amino-1,3-dihydroxyoctadecane> 
• 131606-91-2 (2R,3E)-2-(methoxymethoxy)-1-trityloxyoctadec-3-ene 
• 118106-53-9 (2S,3R,2'R,3'E)-2-N-(2'-hydroxy-3'-octadecenoyl)-[2-amino-octadecan-1,3-diol] 

Relevant academic research and scientific papers

Total synthesis of symbioramide: A flexible approach for the efficient preparation of structural isomers

A concise, enantioselective total synthesis of symbioramide, starting from simple achiral compounds and racemic α-amino-β-keto ester derivatives is reported. This highly flexible strategy allowed the efficient preparation of seven structural isomers of the natural product as well. The synthesis relies on a convergent route that involves the efficient stereoselective reduction of a α-keto-β-yne ester, and the dynamic kinetic resolution of an α-amino-β-keto ester through ruthenium-mediated asymmetric hydrogenation. Copyright

Total Synthesis of Symbioramide, a Novel Ca(2+)-ATPase Activator from Symbiodinium sp.

The first total synthesis of symbioramide 1 has been accomplished by the coupling of D-erythro-dihydrosphingosine with an unusual, chiral α-hydroxy-β,γ-unsaturated fatty acid prepared from L-ascorbic acid, and simultaneously established the complete stereostructure of 1 to be (2S,2'R,3R,3'E)-N-(2'-hydroxyoctadec-3'-enoyl)dihydrosphingosine.

First Total Synthesis of Symbioramide, a Novel Ca2+-ATPase Activator from Symbiodinium sp.

The first total synthesis of symbioramide (1) is described and simultaneously established the complete stereostructure of 1 to be (2S,3R,2'R,3'E)-N-(2'-hydroxy-3'-octadecenoyl)-dihydrosphingosine.