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Upstream product

• 67-56-1 methanol 
• 150178-55-5 (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl (2R,3E)-2-hydroxy-3-octadecenoate 
• 150178-56-6 (1R,2S)-2-phenyl-1-cyclohexyl (2R,3E)-2-hydroxy-3-octadecenoate 
• 1083079-89-3 1-O-(α-D-glucopyranosyl)-(2S,3R,4E,8E,10E)-2-[(2'R,3'E)-2'-hydroxyoctadec-3'-enoylamino]-9-methyloctadeca-4,8,10-triene-1,3-diol 
• 1184182-47-5 (2R,3E)-2-hydroxy-N-[(2S,3R,4E)-1-β-D-glucopyranosyloxy-3-hydroxy-9-methylene-8-oxooctadec-4-en-2-yl]octadec-3-enamide 
• 1184182-48-6 (2R,3E)-2-hydroxy-N-[(2S,3R,4E,8E)-1-β-D-glucopyranosyloxy-3-hydroxy-9-methylheptadec-4,8-dien-2-yl]octadec-3-enamide 
• 1184182-50-0 (2R,3E)-2-hydroxy-N-[(2S,3R,4E,8Z)-1-β-D-glucopyranosyloxy-3-hydroxyoctadec-4,8-dien-2-yl]octadec-3-enamide 
• 1363377-89-2 1-O-β-D-glucopyranosyl-(2S,3S,4E,9E)-2-[(2R,3E)-2-hydroxyoctadec-3-enoylamino]-10-methyl-octadeca-4,9-diene-1,3-diol 
• 1283114-63-5 (2R,3E)-2-hydroxy-N-[(2S,3R,4E,8Z)-1-β-D-glucopyranosyloxy-3-hydroxyhexadeca-4,8-dien-2-yl]octadec-3-enamide 

Relevant academic research and scientific papers

Ceramide and cerebrosides from the octocoral sarcophyton ehrenbergi

Chemical investigation of the octocoral Sarcophyton ehrenbergi, collected at the Dongsha Islands, Taiwan, has led to the isolation of a known ceramide (1) and two new cerebrosides, sarcoehrenosides A (2)andB(4), along with three known cerebrosides (3, 5,

Cerebrosides and 2-pyridone alkaloids from the halotolerant fungus Penicillium chrysogenum grown in a hypersaline medium

Five new cerebrosides, chrysogesides A-E (1-5), and two new 2-pyridone alkaloids, chrysogedones A and B (6 and 7), were isolated from the fermentation broth of Penicillium chrysogenum PXP-55, a halotolerant fungus grown in a hypersaline medium. Among them, chrysogesides B-D (2-4) are the first cerebrosides that contain an unsaturated C19-fatty acid. Their structures were identified by spectroscopic and chemical methods, including CD spectroscopy as well as the modified Mosher's method. Compound 2 showed antimicrobial activity against Enterobacter aerogenes with an MIC value of 1.72 μM. (Chemical Equation Presented).

Flavusides A and B, antibacterial cerebrosides from the marine-derived fungus Aspergillus flavus

Flavusides A (1) and B (2), two new antibacterial cerebroside derivatives, and the previously described phomaligol A (3), kojic acid (4), methyl kojic acid (5), and dimethyl kojic acid (6) have been isolated from the extract of a marine isolate of the fungus Aspergillus flavus. The structure and absolute stereochemistry of two cerebrosides were assigned on the basis of NMR and Tandem FAB-MS/MS experiments. Compounds 1, 2, and 3 exhibited a mild antibacterial activity against Staphylococcus aureus, methicillin-resistant S. aureus, and multidrug-resistant S. aureus. The minimum inhibitory concentration (MIC) values for each strain are as follows: compounds 1 and 2 showed 15.6 μg/ml for S. aureus and 31.2 μg/ml for methicillin-resistant S. aureus and multidrug-resistant S. aureus, and compound 3 exhibited 31.2 μg/ml for S. aureus and methicillin-resistant S. aureus and 62.5 μg/ml for multidrug-resistant S. aureus.

Cerebrosides of the halotolerant fungus Alternaria raphani isolated from a sea salt field

In order to search for structurally novel and bioactive natural compounds from marine-derived fungi, a halotolerant fungal strain (THW-18) identified as Alternaria raphani was isolated from sediment collected in the Hongdao sea salt field. From the ethyl