131613-47-3

Upstream product

• 87568-67-0 p-nitrobenzyl (1'RS,5RS,6SR)-6-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 75-08-1 ethanethiol 

Downstream Products

• 115026-37-4 p-nitrobenzyl (2RS,3SR,5SR,6RS)-3-acetoxy-3-ethylsulphonyl-6-<(1RS)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-7-oxo-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 115026-37-4 p-nitrobenzyl (2RS,3RS,5SR,6RS)-3-acetoxy-3-ethylsulphonyl-6-<(1RS)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-7-oxo-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 115026-37-4 (5R,6S)-3-Acetoxy-3-ethanesulfonyl-6-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-7-oxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 4-nitro-benzyl ester 
• 115026-38-5 p-nitrobenzyl (5RS,6SR)-3-acetoxy-6-<(1RS)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 

Relevant academic research and scientific papers

SYNTHESIS OF THE 3-ACETOXY-7-OXO-1-AZABICYCLOHEPT-2-ENE-CARBOXYLATE SYSTEM

Lead tetraacetate oxidation of the carbapenem derived ethanethiol adduct (4-6) gave the corresponding 3-acetoxy-3-ethylthio derivatives (7-9).Oxidation to sulphone and elimination of ethylsulphinic acid furnished the 3-acetoxy-7-oxo-1-azabicyclohep