87568-67-0

Upstream product

• 107685-91-6 p-nitrobenzyl (1'RS,3SR,4RS)-<4-allyl-3-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-2-oxoazetidin-1-yl>(triphenylphosphoranylidene)acetate 
• 87568-66-9 {(2R,3R)-2-(2,2-Dimethoxy-ethyl)-3-[(S)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid 4-nitro-benzyl ester 
• 87568-69-2 (+/-)-1-(hydroxy(((p-nitrobenzyl)oxy)carbonyl)methyl)-4(R*)-(2,2-dimethoxyethyl)-3(R*)-(1(S*)-((((p-nitrobenzyl)oxy)carbonyl)oxy)ethyl)azetidin-2-one 
• 77447-98-4 (+/-)-4β-(2,2-dimethoxyethyl)-3β-<(1S^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one 
• 64370-35-0 p-nitrobenzyl glyoxylate 
• 107685-90-5 [(3R,4R)-3-[(S)-1-(4-Nitro-benzyloxycarbonyloxy)-ethyl]-2-oxo-4-(2-oxo-ethyl)-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid 4-nitro-benzyl ester 
• 107685-89-2 {(2R,3S)-2-Allyl-3-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-chloro-acetic acid 4-nitro-benzyl ester 
• 107685-88-1 p-nitrobenzyl (1'RS,3SR,4RS)-<4-allyl-3-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-2-oxoazetidin-1-yl>hydroxyacetate 
• 80391-28-2 (1'RS,3SR,4RS)-4-allyl-3-<1-(p-nitrobenzyloxycarbonyloxy)-ethyl>azetidin-2-one 
• 107668-31-5 (1'RS,3SR,4RS)-4-allyl-1-(dimethyl-t-butylsilyl)-3-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-azetidin-2-one 
• 4457-32-3 4-nitrobenzyl chloroformate 
• 77526-92-2 (1'RS,3SR,4RS)-4-allyl-1-(dimethyl-t-butylsilyl)-3-(1-hydroxyethyl)-azetidin-2-one 

Downstream Products

• 107685-93-8 p-nitrobenzyl (1'RS,3aRS,4aRS,5SR,7aRS)-3a,4,4a,5,6,7a-hexahydro-5-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-6-oxo-3H-azeto<1',2':1,5>pyrrolo<2,3-c>pyrazole-7a-carboxylate 
• 115026-36-3 (5R,6S)-3-Ethylsulfanyl-6-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-7-oxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 4-nitro-benzyl ester 
• 87638-51-5 (+/-)-p-nitrobenzyl 6(R*)-(1(S*)-((((p-nitronbenzyl)oxy)carbonyl)oxy)ethyl)-2-(phenylthio)-1-carbapenam-3-carboxylate 
• 87568-68-1 (+/-)-p-nitrobenzyl 6(R*)-(1(S*)-((((p-nitronbenzyl)oxy)carbonyl)oxy)ethyl)-2-(phenylthio)-1-carbapenam-3-carboxylate 
• 115026-37-4 (5R,6S)-3-Acetoxy-3-ethanesulfonyl-6-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-7-oxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 4-nitro-benzyl ester 
• 115026-38-5 p-nitrobenzyl (5RS,6SR)-3-acetoxy-6-<(1RS)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 107668-32-6 p-nitrobenzyl (1'RS,2SR,4RS,6RS,7SR)-7-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-8-oxo-1-azatricyclo<4.2.0.0^2,4>octane-2-carboxylate 
• 107685-92-7 p-nitrobenzyl 3-methyl-6-<1-(p-nitrobenzyloxycarbonyloxy)ethyl>-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 

Relevant academic research and scientific papers

Olivanic Acid Analogues. Part 4. Cycloaddition Reactions of p-Nitrobenzyl 7-Oxo-1-azabicyclohept-2-ene-2-carboxylate, and Synthesis of the 8-Oxo-1-azatricyclo2,4>octane-2-carboxylate System

p-Nitrobenzyl 7-oxo-1-azabicyclohept-2-ene-2-carboxylate (1) participated in Diels-Alder and 1,3-dipolar cycloaddition reactions, yielding a range of novel polycyclic azetidinone structures.The two 8-oxo-1-azatricyclo2,4>octane-2

Synthesis of β-lactam antibiotics by the sulfeno-cycloamination

A novel efficient beta -lactam synthesis was achieved by two successive processes (sulfeno-cycloamination), addition of phenysulfenyl chloride to alpha , beta -unsaturated amides followed by base treatment. Key synthetic intermediates of monobactams and nocardicin derivatives were obtained via this method. construction of the 1-carbapenam ring system by the sulfenocycloamination is also described.