131613-93-9

Basic information

• Product Name: tert-butyl (4S)-4-{(S)-hydroxy[(2S)-5-oxo-2,5-dihydrofuran-2-yl]methyl}-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
• CAS NO: 131613-93-9
• Molecular Formula: C₁₅H₂₃NO₆
• Molecular Weight: 313.3462
• Mol File: 131613-93-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 476.7°C at 760 mmHg
• Flash Point: 242.1°C
• Density: 1.228g/cm³
• Vapor Pressure: 4.35E-11mmHg at 25°C
• Refractive Index: 1.516
• CAS DataBase Reference: tert-butyl (4S)-4-{(S)-hydroxy[(2S)-5-oxo-2,5-dihydrofuran-2-yl]methyl}-2,2-dimethyl-1,3-oxazolidine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (4S)-4-{(S)-hydroxy[(2S)-5-oxo-2,5-dihydrofuran-2-yl]methyl}-2,2-dimethyl-1,3-oxazolidine-3-carboxylate(131613-93-9)
• EPA Substance Registry System: tert-butyl (4S)-4-{(S)-hydroxy[(2S)-5-oxo-2,5-dihydrofuran-2-yl]methyl}-2,2-dimethyl-1,3-oxazolidine-3-carboxylate(131613-93-9)

Safety Data

• Hazardous Substances Data: 131613-93-9(Hazardous Substances Data)

Usage

General Description

"Tert-butyl (4S)-4-{(S)-hydroxy[(2S)-5-oxo-2,5-dihydrofuran-2-yl]methyl}-2,2-dimethyl-1,3-oxazolidine-3-carboxylate is a complex chemical compound with a molecular structure consisting of a tert-butyl group, a hydroxy group, a dihydrofuran-2-yl group, and an oxazolidine-3-carboxylate group. This chemical has potential applications in pharmaceuticals, due to its unique structure and properties. It may have uses as a building block in the synthesis of various bioactive compounds or as a potential drug candidate itself. Further research and investigation into the properties and potential applications of this chemical compound are necessary to explore its full capabilities and benefits."

Upstream product

• 61550-02-5 (furan-2-yloxy)-trimethylsilane 
• 102308-32-7 (4S)-4-formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Downstream Products

• 136489-91-3 Methyl 1,2,3,4-Tetra-O-acetyl-6-deoxy-6-<(tert-butoxycarbonyl)amino>-α-L-glycero-L-talo-heptopyranuronate 
• 136523-34-7 (R)-tert-Butoxycarbonylamino-((2S,3S,4S,5S,6R)-3,4,5,6-tetraacetoxy-tetrahydro-pyran-2-yl)-acetic acid methyl ester 
• 136598-84-0 (S)-2,2-Dimethyl-4-((2S,3S,4S,5S,6R)-3,4,5,6-tetraacetoxy-tetrahydro-pyran-2-yl)-oxazolidine-3-carboxylic acid tert-butyl ester 
• 136597-85-8 (S)-2,2-Dimethyl-4-[(S)-((2S,3S,4S)-5-oxo-3,4-bis-trimethylsilanyloxy-tetrahydro-furan-2-yl)-trimethylsilanyloxy-methyl]-oxazolidine-3-carboxylic acid tert-butyl ester 
• 136597-88-1 1,2,3,4-Tetra-O-acetyl-6,7-N,O-isopropylidene-6-deoxy-6-<(tert-butoxycarbonyl)amino>-α-L-glycero-L-talo-heptopyranose 
• 136597-86-9 2,3,5-Tris-O-(trimethylsilyl)-6,7-N,O-isopropylidene-6-<(tert-butoxycarbonyl)amino>-6-deoxy-L-glycero-L-talo-heptono-1,4-lactone 

Relevant articles and documents

Total Synthesis of 6-Deoxy-6-aminoheptopyranuronic Acid Derivatives

Two enantio couples of terminal C-glycoyranosyl α-amino acids, namely the aminopyranuronic acid, L-9, D-9 and L-10, D-10, hve been synthesized from serine-derived pair L-2, D-2 by exploiting enantiomerically pure butenolide intermediates 3 and 4.The key synthetic steps involved the sequential antiselective cis dihydroxylation of the butenolide double bond and the clean furaose-to-pyranose ring expansion to construct the sugar skeleton with the proper stereochemistry.In our best performance, homogeneous L-9 was prepared from L-2 in four steps and 10 reactions in 20percent overall yield.

THE FOUR-CARBON ELONGATION OF THREE-CARBON CHIRAL SYNTHONS USING 2-(TRIMETHYLSILOXY)FURAN: HIGHLY STEREOCONTROLLED ENTRY TO ENANTIOMERICALLY PURE SEVEN-CARBON α,β-UNSATURATED 2,3-DIDEOXYALDONOLACTONES

The BF3-promoted addition of 2-(trimethylsiloxy)furan to three carbon synthons derived from D- and L-glyceraldehyde, D- and L-serinal, and imines thereof furnishes C7 α,β-unsaturated 2,3-dideoxy-aldonolactone derivatives in high yield, with very high level of diastereoselection.In all the cases, compounds having 4,5-threo:5,6-erythro relative stereodisposition preferentially emerge from the reactions, accompanied by only marginal amounts of 4,5-erythro:5,6-threo epimers.An empirical rule for the rapid assignment of the configuration at C-4 (γ-carbon) of γ-substituted unsaturated and saturated β-butyrolactones is given, based upon the sign of the optical rotation values.